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Open AccessA geographically-diverse collection of 418 human gut microbiome pathway genome databases
Advances in high-throughput sequencing are resha** how we perceive microbial communities inhabiting the human body, with implications for therapeutic interventions. Several large-scale datasets derived from ...
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Open AccessMetabolic pathways for the whole community
A convergence of high-throughput sequencing and computational power is transforming biology into information science. Despite these technological advances, converting bits and bytes of sequence information int...
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Open AccessMetaPathways: a modular pipeline for constructing pathway/genome databases from environmental sequence information
A central challenge to understanding the ecological and biogeochemical roles of microorganisms in natural and human engineered ecosystems is the reconstruction of metabolic interaction networks from environmen...
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Open AccessExpanding the boundaries of local similarity analysis
Pairwise comparison of time series data for both local and time-lagged relationships is a computationally challenging problem relevant to many fields of inquiry. The Local Similarity Analysis (LSA) statistic i...