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  1. Article

    Open Access

    Aprepitant for refractory cutaneous T-cell lymphoma-associated pruritus: 4 cases and a review of the literature

    Aprepitant is an FDA-approved medication for chemotherapy-induced nausea and vomiting. It blocks substance P binding to neurokinin-1; substance P has been implicated in itch pathways both as a local and global...

    Johanna S. Song, Marianne Tawa, Nicole G. Chau, Thomas S. Kupper in BMC Cancer (2017)

  2. Article

    Open Access

    Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

    Patient selection for phase I trials (PIT) in oncology is challenging. A typical inclusion criterion for PIT is 'life expectancy > 3 months', however the 90 day mortality (90DM) and overall survival (OS) of pa...

    Nicole G Chau, Ana Florescu, Kelvin K Chan, Lisa Wang, Eric X Chen in BMC Cancer (2011)