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  1. Article

    Open Access

    High-Throughput Generation of Bipod (Fab × scFv) Bispecific Antibodies Exploits Differential Chain Expression and Affinity Capture

    Generation of bispecific antibodies (BsAbs) having two unique Fab domains requires heterodimerization of the two heavy chains and pairing of each heavy chain with its cognate light chain. An alternative bispec...

    Thomas C. Nesspor, Kyle Kinealy, Nicholas Mazzanti, Michael D. Diem in Scientific Reports (2020)