6 Result(s)
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Neus Bota-Rabassedas
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Open AccessAuthor Correction: FGF coordinates air sac development by activation of the EGF ligand Vein through the transcription factor PntP2
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Open AccessA collagen glucosyltransferase drives lung adenocarcinoma progression in mice
Cancer cells are a major source of enzymes that modify collagen to create a stiff, fibrotic tumor stroma. High collagen lysyl hydroxylase 2 (LH2) expression promotes metastasis and is correlated with shorter s...
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Open AccessAuthor Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding
In the originally published version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to also include support from the National Ins...
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Open AccessPro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding
Collagen lysyl hydroxylases (LH1-3) are Fe2+- and 2-oxoglutarate (2-OG)-dependent oxygenases that maintain extracellular matrix homeostasis. High LH2 levels cause stable collagen cross-link accumulations that pro...
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Open AccessThy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis
Cancer-associated fibroblasts (CAFs) regulate diverse intratumoral biological programs and can promote or inhibit tumorigenesis, but those CAF populations that negatively impact the clinical outcome of lung ca...
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Open AccessFGF coordinates air sac development by activation of the EGF ligand Vein through the transcription factor PntP2
How several signaling pathways are coordinated to generate complex organs through regulation of tissue growth and patterning is a fundamental question in developmental biology. The larval trachea of Drosophila is...
