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    Article

    Heterogeneity of PD-L1 expression between invasive and lepidic components of lung adenocarcinomas

    The dynamics of PD-L1 expression are poorly understood over the development of lung adenocarcinomas from pre-invasive lesions to fully invasive carcinomas. Given the importance of PD-L1 expression for the sele...

    Antonious Hazim, Neil Majithia, Stephen J. Murphy in Cancer Immunology, Immunotherapy (2021)

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    Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial

    Chemotherapy-induced peripheral neuropathy (CIPN) is a prominent clinical problem, with limited effective therapies. Preliminary non-randomized clinical trial data support that Scrambler Therapy is helpful in ...

    Charles Loprinzi, Jennifer G. Le-Rademacher, Neil Majithia in Supportive Care in Cancer (2020)

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    STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation

    STEAP4 (six-transmembrane epithelial antigen of the prostate 4) is a metalloreductase that has been shown previously to protect cells from inflammatory damage. Genetic variants in STEAP4 have been associated w...

    Hannah M. Gordon, Neil Majithia, Patrick E. MacDonald, Jocelyn E. Manning Fox in Endocrine (2017)

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    Scrambler Therapy for the management of chronic pain

    Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and behavioral strategies exist for the management of this cond...

    Neil Majithia, Thomas J. Smith, Patrick J. Coyne in Supportive Care in Cancer (2016)

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    Zoledronic acid for treatment of osteopenia and osteoporosis in women with primary breast cancer undergoing adjuvant aromatase inhibitor therapy: a 5-year follow-up

    This study was designed to explore whether zoledronic acid could prevent expected loss of bone mineral density (BMD) in postmenopausal women with pre-existing osteopenia or osteoporosis who were initiating adj...

    Neil Majithia, Pamela J. Atherton, Jacqueline M. Lafky in Supportive Care in Cancer (2016)

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    National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons

    Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common and debilitating complications of cancer treatment. Due to a lack of effective management options for patients with CIPN, the Nationa...

    Neil Majithia, Sarah M. Temkin, Kathryn J. Ruddy in Supportive Care in Cancer (2016)

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    Article

    Distinctive Tumor Biology of MSI-High Colorectal Cancer

    High-frequency microsatellite instability (MSI-H) accounts for roughly 15 % of all cases of colorectal cancer (CRC) and results from pathogenic mutations or epigenetic changes in mismatch repair (MMR) proteins...

    Neil Majithia, Benjamin R. Kipp, Axel Grothey in Current Colorectal Cancer Reports (2015)