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    Selective degradation of splicing factor CAPERα by anticancer sulfonamides

    A series of sulfonamides induced the ubiquitin-mediated degradation of the U2AF-related splicing factor, coactivator of activating protein-1 and estrogen receptor α (CAPERα), by promoting direct binding betwee...

    Taisuke Uehara, Yukinori Minoshima, Koji Sagane, Naoko Hata Sugi… in Nature Chemical Biology (2017)