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Article
Enzymatic properties of a non-classical aldoxime dehydratase capable of producing alkyl and arylalkyl nitriles
Nitriles are of significant interest in the flavor and fragrance industries with potential application in cosmetics due to their higher stability than analogous aldehydes. However, the traditional methods to p...
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Article
Role of Esophageal Metal Stents Placement and Combination Therapy in Inoperable Esophageal Carcinoma: A Systematic Review and Meta-analysis
More than 50% of patients with esophageal cancer already have inoperable disease at the time of diagnosis. Controversy surrounds the outcomes of patients with advanced esophageal cancer who receive palliative ...
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Article
Open AccessProtective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
Acute kidney injury is associated with high mortality, especially in intensive care unit patients. The polyol pathway is a metabolic route able to convert glucose into fructose. Here we show the detrimental ro...
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Article
Correction: Corrigendum: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
Nature Communications 4: Article number: 2434 (2013); Published: 10 September 2013; Updated: 4 December 2013 The original version of this Article contained an error in the spelling of the author Philip Ruzycki...
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Article
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
Carbohydrates with high glycaemic index are proposed to promote the development of obesity, insulin resistance and fatty liver, but the mechanism by which this occurs remains unknown. High serum glucose concen...
