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Article
Identification and characterization of an alternative cancer-derived PD-L1 splice variant
Therapeutic blockade of the PD-1/PD-L1 axis is recognized as an effective treatment for numerous cancer types. However, only a subset of patients respond to this treatment, warranting a greater understanding o...
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Article
Open AccessLoss of primary cilia occurs early in breast cancer development
Primary cilia are microtubule-based organelles that protrude from the cell surface. Primary cilia play a critical role in development and disease through regulation of signaling pathways including the Hedgehog...