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    Article

    Identification and characterization of an alternative cancer-derived PD-L1 splice variant

    Therapeutic blockade of the PD-1/PD-L1 axis is recognized as an effective treatment for numerous cancer types. However, only a subset of patients respond to this treatment, warranting a greater understanding o...

    Nadia B. Hassounah, Venkat S. Malladi, Yi Huang in Cancer Immunology, Immunotherapy (2019)

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    Open Access

    Loss of primary cilia occurs early in breast cancer development

    Primary cilia are microtubule-based organelles that protrude from the cell surface. Primary cilia play a critical role in development and disease through regulation of signaling pathways including the Hedgehog...

    Ina Menzl, Lauren Lebeau, Ritu Pandey, Nadia B Hassounah, Frank W Li, Ray Nagle in Cilia (2014)