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Article
GABA transporter 1 transcriptional starting site exhibiting tissue specific difference
GABA transporter 1(GAT1) takes important roles in multiple physiological processes through the uptake and release of GABA, but the regulation of GAT1 gene expression in different tissues is rarely known. To ad...
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Article
Enhancement of germ cell apoptosis induced by ethanol in transgenic mice overexpressing Fas Ligand
It was suggested that chronic ethanol exposure could result in testicular germ cell apoptosis, but the mechanism is still unclear. In the present study, we use a model of transgenic mice ubiquitously overexpre...
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Article
Impaired reproduction in transgenic mice overexpressing γ-aminobutyric acid transporter I (GAT1)
It is well documented that γ-aminobutyric acid (GABA) system existed in reproductive organs. Recent researches showed that GABAA and GABAB receptors were present in testis and sperm, and might mediate the acrosom...
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Article
Open AccessTwo-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase
Enzymatic biodiesel production by transesterification in solvent media has been investigated intensively, but glycerol, as a by-product, could block the immobilized enzyme and excess n-hexane, as a solution aid, ...
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Article
Open AccessSeroprevalence of Toxoplasma gondii infection in slaughtered chickens, ducks, and geese in Shenyang, northeastern China
In recent years, investigations of Toxoplasma gondii infection in poultry (chickens, ducks, and geese) have been reported worldwide, including China. However, little is known about the prevalence of T. gondii inf...
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Article
Open AccessSeroprevalence of Toxoplasma gondii in slaughtered horses and donkeys in Liaoning province, northeastern China
Toxoplasma gondii is an important zoonotic pathogen infecting humans and almost all warm-blooded animals. The most common sources of human infection are ingestion of tissue cysts in raw or undercooked meat. Howev...
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Article
Open AccessCommon rs7138803 variant of FAIM2 and obesity in Han Chinese
Obesity causes severe healthcare problem worldwide leading to numerous diseases, such as cardiovascular diseases and diabetes mellitus. Previous Genome-Wide Association Study (GWAS) identified an association b...
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Article
Open AccessStructure and domain organization of Drosophila Tudor
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Article
Open AccessValsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction via Casein Kinase 2
Myocardial infarction (MI) results in an increased susceptibility to ventricular arrhythmias, due in part to decreased inward-rectifier K+ current (IK1), which is mediated primarily by the Kir2.1 protein. The ...
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Article
Open AccessStructure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
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Article
Open AccessIdentification of a novel cathelicidin antimicrobial peptide from ducks and determination of its functional activity and antibacterial mechanism
The family of antimicrobial peptide, cathelicidins, which plays important roles against infections in animals, has been identified from many species. Here, we identified a novel avian cathelicidin ortholog fro...
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Article
Open AccessStatistical analysis of ionospheric mid-latitude trough over the Northern Hemisphere derived from GPS total electron content data
This study statistically investigated the seasonal variation, magnetic local time (MLT) variation, geomagnetic activity dependence, and solar activity dependence of the mid-latitude trough using GPS total elec...
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Chapter and Conference Paper
A Cross-Cultural Adaptation in Reporting Perinatal Safety Events
Incident reporting enables clinicians to examine historical patient safety events and to target different levels of analysis toward actionable knowledge. The cross-cultural adaptation of reporting instruments ...
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Article
Open AccessSemaphorin 3A attenuates cardiac autonomic disorders and reduces inducible ventricular arrhythmias in rats with experimental myocardial infarction
To investigate the effects of semaphorin 3A (sema 3A) on cardiac autonomic regulation and subsequent ventricular arrhythmias (VAs) in post-infarcted hearts.
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Article
Open AccessDoxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2
Chemotherapies often induce drug-resistance in cancer cells and simultaneously stimulate proliferation and activation of Myeloid-Derived Suppressor Cells (MDSCs) to inhibit anti-tumor T cells, thus result in p...
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Article
Open AccessSeroprevalence and genotypes of Toxoplasma gondii isolated from pigs intended for human consumption in Liaoning province, northeastern China
Genetic information for Toxoplasma gondii isolates from pigs in eastern, south, and southwestern regions of China has been reported previously. However, there are no data from pigs in the northeastern area of the...
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Article
Open AccessDesign, biological evaluation and 3D QSAR studies of novel dioxin-containing pyrazoline derivatives with thiourea skeleton as selective HER-2 inhibitors
A series of novel dioxin-containing pyrazoline derivatives with thiourea skeleton have been designed, synthesized and evaluated for their EGFR/HER-2 inhibitory and anti-proliferation activities. A majority of ...
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Article
Open AccessStatistical analysis of the mid-latitude trough position during different categories of magnetic storms and different storm intensities
The ionospheric mid-latitude trough minimum position as a function of geomagnetic storm time is identified and investigated statistically in terms of the category and the intensity of storms. The data of ion d...
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Article
Open AccessCompound danshen drip** pills modulate the perturbed energy metabolism in a rat model of acute myocardial ischemia
The continuous administration of compound danshen drip** pills (CDDP) showed good efficacy in relieving myocardial ischemia clinically. To probe the underlying mechanism, metabolic features were evaluated in...
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Article
Open AccessIn vitro and in vivo antibacterial effect of NZ2114 against Streptococcus suis type 2 infection in mice peritonitis models
NZ2114 is a promising candidate for therapeutic application owing to potent activity to gram-positive bacterium such as Streptococcus pneumoniae and Staphylococcus aureus. This work is the first report to describ...