![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Apoptosis and neutrophils in the regulation of Ph-positive myeloid cell proliferation and differentiation ex vivo
Ex vivo proliferation and differentiation of Philadelphia chromosome-positive (Ph+) human myeloid cells (Ph+ cells) from chronic myeloid leukemia (CML) proceed via alternation stages of cell proliferation and neu...
-
Article
Binding and transfer of an oligodeoxynucleotide containing the translation initiation site of the BCL2 mRNA into K562 cells
A study was conducted of the interaction of an octadecameric oligodeoxynucleotide (dON) containing the BCL2 mRNA translation start with K562 cells. Both in solution and upon lipofection, the binding of dON used a...
-
Article
Alkylation of nucleic acids and their components
In water at pH 5–6,γ-(N-β-chloroethyl-N-methylamino)propylphthalimide (I) alkylates guanosine to give 7-{β-[N-methyl-N-(γ-phthalylimidopropyl)amino]ethyl} guanosine. The latter is converted to 7-{β-[N-methyl-N-(γ
-
Article
Alkylation of nucleic acids and their components
N-β-Chloroethyl-N-methyl-1,3-propylenediamine alkylates guanosine and the guanine in transfer RNA to give 7-[β-(N-γ-aminopropyl-N-methylamino)ethyl]guanosine and the similarly alkylated transfer RNA. The alkylati...
-
Article
Complementaeily addressed alkylation of ribosomal rna with 2′, 3′-o-[4- (chloroethyl-methylamino) benzylidene]hexaadenylate
-
Article
2′,3′-O-[p-(chloroethylmethylamino)benzylidene] tRNA — An addressing reagent with an alkylating grou** on the acceptor end of tRNA
-
Article
Alkylation of nucleic acids and their components
Guanosine, cytidine, inosine, and thymine react with 4-[N-(β-chloroethyl)-N-methylamino]-benzaldehyde to give 7-alkylguanosine, 3-alkylcytidine, 1-alkylinosine, and 1-alkylthymine, respectively. The order of reac...
-
Article
Studies on ceramidone derivatives
The synthesis, arylamination and other reactions of ceramid-9-one are described. 8-Hydroxyceramid-9-one is converted to the corresponding 8-arylaminoceramid-9-one by heating with excess aromatic amine in the p...
-
Article
Identification, separation, and quantitative analysis of derivatives of nucleosides and nucleotides by thin-layer chromatography on cellulose
The thin-layer chromatography of nucleoside and nucleotide derivatives on cellulose has been carried out, and R f values and conditions for the separation and quantitative analy...
-
Article
Preparative method of obtaining guanosine 5′-triphosphate
1. The kinetics of the formation of guanosine 5′-triphosphate, 5′-diphosphate, and 5′-monophosphate in the reaction of the morpholide of guanosine 5′-monophosphate with bis-(tributylammonium) pyrophosphate in ...