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Open AccessOxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking
As opioid-related fatalities continue to rise, the need for novel opioid use disorder (OUD) treatments could not be more urgent. Two separate hypothalamic neuropeptide systems have shown promise in preclinical...
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Open AccessA common limiter circuit for opioid choice and relapse identified in a rodent addiction model
Activity in numerous brain regions drives heroin seeking, but no circuits that limit heroin seeking have been identified. Furthermore, the neural circuits controlling opioid choice are unknown. In this study, ...
