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Article
Interleukin-1β (187–207)-Induced Hyperthermia is Inhibited by Interleukin-1β (193–195) in Rats
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine, which plays an important role in the immune response and signal transduction both in the periphery and the central nervous system (CNS). Various diseases ...
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Article
Suppression of the proliferation of human U-87 MG glioblastoma cells by new antagonists of growth hormone-releasing hormone in vivo and in vitro
Five-year survival of patients afflicted with glioblastoma multiforme (GBM) is rare, making this cancer one of the most feared malignancies. Previously, we reported that growth hormone-releasing hormone (GHRH)...
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Article
Ghrelin and Nicotine Stimulate Equally the Dopamine Release in the Rat Amygdala
The orexigenic peptide ghrelin plays a prominent role in the regulation of energy balance and in the mediation of reward processes and reinforcement for addictive drugs, such as nicotine. Nicotine is the princ...
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Article
The Effects of Endomorphins on Striatal [3H]Gaba Release Induced by Electrical Stimulation: An In vitro Superfusion Study in Rats
The endomorphins (EM1 and EM2) are selective endogenous ligands for mu-opioid receptors (MOR1 and MOR2) with neurotransmitter and neuromodulator roles in mammals. In the present study we investigated the poten...
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Article
The Effects of Corticoptropin-Releasing Factor and the Urocortins on Striatal Dopamine Release Induced by Electrical Stimulation—An in vitro Superfusion Study
The members of the CRF peptide family, corticotropin-releasing factor (CRF), urocortin I (Ucn I), urocortin II (Ucn II) and urocortin III (Ucn III) coordinate endocrine and behavioral responses to stress. CRF ...
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Article
Effects of endomorphin-1 on open-field behavior and on the hypothalamic-pituitary-adrenal system
The effects of endomorphin-1 (EM1) on behavioral responses and on the hypothalamic-pituitary-adrenal system were investigated in mice. Locomotor activity was measured in an “open-field” apparatus, with paralle...
