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    Article

    Antiamnesic properties of analogs and mimetics of the tripeptide human urocortin 3

    Amnesia is a deficit in memory caused by brain damage, disease, or trauma. Until now, there are no successful medications on the drug market available to treat amnesia. Short analogs and mimetics of human uroc...

    Gyula Telegdy, Anita Kármen Kovács, Kinga Rákosi, Márta Zarándi in Amino Acids (2016)

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    Article

    Suppression of the proliferation of human U-87 MG glioblastoma cells by new antagonists of growth hormone-releasing hormone in vivo and in vitro

    Five-year survival of patients afflicted with glioblastoma multiforme (GBM) is rare, making this cancer one of the most feared malignancies. Previously, we reported that growth hormone-releasing hormone (GHRH)...

    Miklos Jaszberenyi, Andrew V. Schally, Norman L. Block, Marta Zarandi in Targeted Oncology (2013)

  3. Article

    Antagonists of growth hormone releasing hormone (GHRH) given before whole body radiation lead to modulation of radiation response and organ-specific changes in the expression of angiogenesis

    This study seeks to determine if growth hormone-releasing hormone (GHRH) antagonist, JMR-132, increases survival when given before whole body radiation.

    May Abdel-Wahab, Andrew V. Schally, Ferenc G. Rick in Journal of Radiation Oncology (2012)

  4. Article

    Open Access

    Antiproliferative effect of growth hormone-releasing hormone (GHRH) antagonist on ovarian cancer cells through the EGFR-Akt pathway

    Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers.

    Jian Guo, Andrew V Schally, Marta Zarandi in Reproductive Biology and Endocrinology (2010)

  5. Article

    Open Access

    The Immunohistochemical Expression of Growth Hormone-Releasing Hormone Receptor Splice Variant 1 Is a Favorable Prognostic Marker in Colorectal Cancer

    Hypothalamic growth hormone (GH)-releasing hormone (GHRH) regulates the release of GH from the pituitary gland. The receptors for GHRH (GHRH-R) are expressed predominantly in the pituitary. Recent evidence dem...

    Elena Theophanous, Constantina Petraki, Andreas Scorilas in Molecular Medicine (2009)

  6. No Access

    Article

    Aged synthetic human amyloid β-peptide 1-42 and related fragments induce direct acetylcholine release from rat basal forebrain tissue slices

    The direct effects of synthetic human amyloid β-peptide 1–42 (Aβ1–42), scrambled Aβ1–42 (MOD1 and MOD2), and related fragments (Aβ31–35, Aβ34–39, and Aβ17–21), either freshly dissolved (non-aged) or aged for 2...

    Mónika Forgon M.D., Z. Farkas, Magdolna Pákáski, Márta Zarándi in Acta Biologica Hungarica (1998)