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Article
Open AccessTranscriptome signatures of class I and III stress response deregulation in Lactobacillus plantarum reveal pleiotropic adaptation
To cope with environmental challenges bacteria possess sophisticated defense mechanisms that involve stress-induced adaptive responses. The canonical stress regulators CtsR and HrcA play a central role in the ...
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Article
Open AccessImpact of 4 Lactobacillus plantarum capsular polysaccharide clusters on surface glycan composition and host cell signaling
Bacterial cell surface-associated polysaccharides are involved in the interactions of bacteria with their environment and play an important role in the communication between pathogenic bacteria and their host ...
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Article
Open AccessLactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching
Specific strains of Lactobacillus plantarum are marketed as health-promoting probiotics. The role and interplay of cell-wall compounds like wall- and lipo-teichoic acids (WTA and LTA) in bacterial physiology and ...
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Article
Open AccessFrom transcriptional landscapes to the identification of biomarkers for robustness
The ability of microorganisms to adapt to changing environments and gain cell robustness, challenges the prediction of their history-dependent behaviour. Using our model organism Bacillus cereus, a notorious Gram...
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Article
Open AccessThioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1
Thioredoxin (TRX) is a powerful disulfide oxido-reductase that catalyzes a wide spectrum of redox reactions in the cell. The aim of this study is to elucidate the role of the TRX system in the oxidative stress...