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Article

Relative roles of the different Pax6 domains for pancreatic alpha cell development

The transcription factor Pax6 functions in the specification and maintenance of the differentiated cell lineages in the endocrine pancreas. It has two DNA binding domains, the paired domain and the homeodomain...

Petra Dames, Ramona Puff, Michaela Weise, Klaus G Parhofer… in BMC Developmental Biology (2010)