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Article
Open AccessGlucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer
Cancer cells depend on nicotinamide adenine dinucleotide phosphate (NADPH) to combat oxidative stress and support reductive biosynthesis. One major NADPH production route is the oxidative pentose phosphate pat...
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Article
A systems identification approach using Bayes factors to deconstruct the brain bases of emotion regulation
Cognitive reappraisal is fundamental to cognitive therapies and everyday emotion regulation. Analyses using Bayes factors and an axiomatic systems identification approach identified four reappraisal-related co...
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Article
Privacy preserving cold-start recommendation for out-of-matrix users via content baskets
Guest users, single-time clients who use an online service anonymously without prior registration, are common in real-world recommendation applications, requiring industrial recommendation systems to handle th...
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Article
Nanomedicine platform for targeting activated neutrophils and neutrophil–platelet complexes using an α1-antitrypsin-derived peptide motif
Targeted drug delivery to disease-associated activated neutrophils can provide novel therapeutic opportunities while avoiding systemic effects on immune functions. We created a nanomedicine platform that uniqu...
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Article
Disruption in Pavlovian-Instrumental Transfer as a Function of Depression and Anxiety
The Pavlovian-Instrumental Transfer (PIT) paradigm examines probabilistic and reinforcement learning. Disruptions in mechanisms that mediate PIT (i.e., cues not triggering adaptive behaviors) are thought to be...
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Scapholunate Ligament Injuries in Baseball
Scapholunate ligament injuries are a frequent cause of wrist pain, instability, and dysfunction. As the primary stabilizer of the scapholunate joint, the scapholunate ligament plays an integral role in normal ...
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Article
Correction to: Novel Spaced Repetition Flashcard System for the In-training Examination for Obstetrics and Gynecology
A correction to this paper has been published: https://doi.org/10.1007/s40670-021-01344-5
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Article
Novel Spaced Repetition Flashcard System for the In-training Examination for Obstetrics and Gynecology
Electronic flashcards allow repeated information exposure over time along with active recall. It is increasingly used for self-study by medical students but remains poorly implemented for graduate medical educ...
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Article
Spaced Repetition Flashcards for Teaching Medical Students Psychiatry
Retrieval practice, often using electronic flashcards, is increasingly utilized among medical students for self-study. In this study, the authors evaluated usage and satisfaction with electronic flashcards bas...
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Article
Prostate-Specific Membrane Antigen (PSMA)-Targeted Radionuclide Therapies for Prostate Cancer
Prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy (TRT) is a promising investigational treatment for metastatic castration-resistant prostate cancer (mCRPC). This review describes the ava...
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Article
Open AccessIntravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve ‘golden hour’ survival in a porcine model of traumatic arterial hemorrhage
Traumatic non-compressible hemorrhage is a leading cause of civilian and military mortality and its treatment requires massive transfusion of blood components, especially platelets. However, in austere civilia...
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Article
Managing In-Session “Surprises:” Provider Responses to Emergent Life Events during Evidence-Based Treatment Implementation
This study aimed to: (1) pilot a psychotherapy coding system for provider responses to emergent life events (ELEs; unexpected events that have a significant negative impact on the client), (2) examine the imp...
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Article
Open AccessCbx3/HP1γ deficiency confers enhanced tumor-killing capacity on CD8+ T cells
Cbx3/HP1γ is a histone reader whose function in the immune system is not completely understood. Here, we demonstrate that in CD8+ T cells, Cbx3/HP1γ insufficiency leads to chromatin remodeling accompanied by enha...
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Article
The Influence of Second Matrix Layer on Microbial Whole-Cell Target Spots Unclassified by MALDI-TOFMS
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Article
Open AccessPercutaneous epiphysiodesis using transphyseal screws for limb-length discrepancies: high variability among growth predictor models
Percutaneous epiphysiodesis using transphyseal screws (PETS) was developed as a minimally invasive outpatient procedure to address limb-length discrepancy (LLD) that allowed immediate postoperative weight bear...
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Article
Level-Rank Duality via Tensor Categories
We give a new way to derive branching rules for the conformal embedding $$(\hat{\mathfrak{sl}}_n)_m\oplus(\hat{\mathfrak{sl}}_m)_n\sub...
