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within Michael Lindner Remove this filter Pneumology/Respiratory System Remove this filter

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  1. Article

    Open Access

    Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis

    Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to f...

    Mareike Lehmann, Lara Buhl, Hani N. Alsafadi, Stephan Klee… in Respiratory Research (2018)

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  2. Article

    Open Access

    FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis

    In idiopathic pulmonary fibrosis (IPF), fibroblasts gain a more migratory phenotype and excessively secrete extracellular matrix (ECM), ultimately leading to alveolar scarring and progressive dyspnea. Here, we...

    Larissa Knüppel, Katharina Heinzelmann, Michael Lindner… in Respiratory Research (2018)

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