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    Article

    Genetics of mouse behavioral and peripheral neural responses to sucrose

    Mice of the C57BL/6ByJ (B6) strain have higher consumption of sucrose, and stronger peripheral neural responses to it, than do mice of the 129P3/J (129) strain. To identify quantitative trait loci (QTLs) respo...

    Cailu Lin, Masashi Inoue, **a Li, Natalia P. Bosak, Yutaka Ishiwatari in Mammalian Genome (2021)

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    Article

    Genetic controls of Tas1r3-independent sucrose consumption in mice

    We have previously used crosses between C57BL/6ByJ (B6) and 129P3/J (129) inbred strains to map a quantitative trait locus (QTL) on mouse chromosome (Chr) 4 that affects behavioral and neural responses to sucr...

    Cailu Lin, Michael G. Tordoff, **a Li, Natalia P. Bosak, Masashi Inoue in Mammalian Genome (2021)

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    Article

    Genetic loci affecting body weight and fatness in a C57BL/6J × PWK/PhJ mouse intercross

    To determine the genetic variation that contributes to body composition in the mouse, we interbred a wild-derived strain (PWK/PhJ; PWK) with a common laboratory strain (C57BL/6J; B6). The parental, F1, and F2 mic...

    Hongguang Shao, Danielle R. Reed, Michael G. Tordoff in Mammalian Genome (2007)

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    Article

    A locus on mouse Chromosome 9 (Adip5) affects the relative weight of the gonadal but not retroperitoneal adipose depot

    To identify the gene or genes on mouse Chromosome 9 that contribute to strain differences in fatness, we conducted an expanded map** analysis to better define the region where suggestive linkage was found, u...

    Amanda H. McDaniel, **a Li, Michael G. Tordoff, Alexander A. Bachmanov in Mammalian Genome (2006)

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    Article

    Quantitative trait loci for individual adipose depot weights in C57BL/6ByJ x 129P3/J F2 mice

    To understand how genotype influences fat patterning and obesity, we conducted an autosomal genome scan using male and female F2 hybrids between the C57BL/6ByJ and 129P3/J parental mouse strains. Mice were studie...

    Danielle R. Reed, Amanda H. McDaniel, **a Li, Michael G. Tordoff in Mammalian Genome (2006)

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    Article

    Loci on Chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains

    Mice have proved to be a powerful model organism for understanding obesity in humans. Single gene mutants and genetically modified mice have been used to identify obesity genes, and the discovery of loci for p...

    Danielle R. Reed, **a Li, Amanda H. McDaniel, Ke Lu, Shanru Li in Mammalian Genome (2003)

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    Genetic, physical, and comparative map of the subtelomeric region of mouse Chromosome 4

    The subtelomeric region of mouse chromosome (Chr) 4 harbors loci with effects on behavior, development, and disease susceptibility. Regions near the telomeres are more difficult to map and characterize than ot...

    **a Li, Alexander A. Bachmanov, Shanru Li, Zhenyu Chen in Mammalian Genome (2002)

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    Article

    High-resolution genetic map** of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4

    The Sac (saccharin preference) locus affecting mouse behavioral and neural responsiveness to sweeteners has been mapped to distal Chr 4. A putative sweet taste receptor, T1R1, has been recently cloned, and the g...

    **a Li, Masashi Inoue, Danielle R. Reed, Taufiqul Huque in Mammalian Genome (2001)

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    Article

    Sucrose consumption in mice: Major influence of two genetic Loci affecting peripheral sensory responses

    Individual variability in sucrose consumption is prominent in humans and other species. To investigate the genetic contribution to this complex behavior, we conducted behavioral, electrophysiological, and gene...

    Alexander A. Bachmanov, Danielle R. Reed, Yuro Ninomiya, Masashi Inoue in Mammalian Genome (1997)