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Open AccessClinical characteristics and management of patients with nonalcoholic steatohepatitis in a real-world setting: analysis of the Ipsos NASH therapy monitor database
Nonalcoholic steatohepatitis (NASH) is the more severe, inflammatory type of nonalcoholic fatty liver disease (NAFLD). NASH, a leading indication for liver transplantation, is growing in prevalence. The extent...
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Article
Nonalcoholic fatty liver disease: impact on healthcare resource utilization, liver transplantation and mortality in a large, integrated healthcare system
NAFLD is the most prevalent liver disease globally, affecting 20% of the world population. Healthcare resource utilization (HRU) attributable to NAFLD has been difficult to define.
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Introduction
The recent advent of high precision antihydrogen spectroscopy opens the way to stringent experimental tests on pure antimatter systems of the fundamental principles underlying particle physics and general rela...
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Summary and Outlook
The main themes of the book are summarised, with a critical assessment of the potential of antihydrogen experiments to test the fundamental principles of quantum field theory and general relativity. Future pro...
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Other Antimatter Species
In this chapter, some present and future possibilities for testing fundamental physics principles using antimatter species other than antihydrogen are briefly discussed.
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Antihydrogen
In this chapter, the implications of the ALPHA antihydrogen spectroscopy programme for testing fundamental physical principles are analysed in detail. Explicit calculations are given for the dependence on poss...
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Fundamental Principles
This chapter presents a theoretical review of the role of antiparticles, causality and fundamental symmetries in local relativistic quantum field theory, together with a discussion of the theory of time measur...
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Article
Liver Allocation Policies in the USA: Past, Present, and the Future
Identifying the optimal allocation policy with regard to hepatocellular carcinoma has been a persistent and evolving challenge. The current criteria for LT for HCC endorsed by the United Network of Organ Shari...
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Article
Exploring ironmaking practices at Meroe, Sudan—a comparative analysis of archaeological and experimental data
Recent excavations of a Late to Post-Meroitic furnace workshop at Meroe, Sudan prompted questions concerning the use of some of its unusual design features and the nature of ironmaking practice. To begin addre...
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Article
Surgical Issues in NASH: Bariatric Surgery and Liver Transplantation
The rising prevalence of obesity in general and non-alcoholic steatohepatitis (NASH) specifically as an indication for liver transplantation has occurred in parallel with an increase in the consideration and p...
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Article
Open AccessClosing in on the properties of antihydrogen
Recent achievements leading, amongst other things, to the observation of the two-photon 1S–2S transition in antihydrogen are reviewed. We summarise some of the technical advances that were necessary to facili...
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Article
Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah
Biliary tract cancers (BTC) including, cholangiocarcinoma (CC) and gallbladder cancer (GBC), are rare and highly fatal malignancies. The etiology and inherited susceptibility of both malignancies are poorly un...
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Article
An Update of Liver Transplantation for Nonalcoholic Steatohepatitis
Nonalcoholic steatohepatitis (NASH), obesity, and the metabolic syndrome are highly prevalent before and after liver transplantation, with NASH currently the second most common indication. This review consider...
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Article
Progress towards microwave spectroscopy of trapped antihydrogen
Precision comparisons of hyperfine intervals in atomic hydrogen and antihydrogen are expected to yield experimental tests of the CPT theorem. The CERN-based ALPHA collaboration has initiated a program of study...
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Article
Antihydrogen detection in ALPHA
The ALPHA project is an international collaboration, based at CERN, with the experimental goal of performing precision spectroscopic measurements on antihydrogen. As part of this endeavor, the ALPHA experiment...
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Article
Compression of positron clouds using rotating wall electric fields
An asymmetric dipolar rotating electric field can be used to compress a trapped cloud of positrons when applied with a frequency close that of their axial bounce, and in the presence of a low pressure molecula...
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Article
Genetic Variation in the Peroxisome Proliferator Activated Receptor-Gamma Gene Is Associated with Histologically Advanced NAFLD
The peroxisome proliferator activated receptor-gamma (PPARG) is a nuclear receptor that regulates adipocyte differentiation, insulin sensitivity and lipid metabolism, thus, it represents a good candidate gene for...
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Article
NAFLD and Insulin Resistance Do Not Increase the Risk of Postoperative Complications Among Patients Undergoing Bariatric Surgery—A Prospective Analysis
Nonalcoholic fatty liver disease (NAFLD) and insulin resistance are common consequences of obesity and are highly prevalent among patients undergoing bariatric surgery. Insulin resistance and NAFLD have been r...
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Article
Hepatic Gene Networks in Morbidly Obese Patients With Nonalcoholic Fatty Liver Disease
Genetic factors alter the risk for nonalcoholic fatty liver disease (NAFLD). We sought to identify NAFLD-associated genes and elucidate gene networks and pathways involved in the pathogenesis of NAFLD.
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Article
Approach to recurrent hepatitis C following liver transplantation
Hepatitis C-associated liver failure is the most common indication for liver transplantation. Histologic evidence of recurrence is apparent in approximately 50% of hepatitis C virus (HCV)-infected recipients i...