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  1. Article

    Open Access

    Clinical characteristics and management of patients with nonalcoholic steatohepatitis in a real-world setting: analysis of the Ipsos NASH therapy monitor database

    Nonalcoholic steatohepatitis (NASH) is the more severe, inflammatory type of nonalcoholic fatty liver disease (NAFLD). NASH, a leading indication for liver transplantation, is growing in prevalence. The extent...

    Karishma Shelley, Amy Articolo, Rakesh Luthra, Michael Charlton in BMC Gastroenterology (2023)

  2. No Access

    Article

    Nonalcoholic fatty liver disease: impact on healthcare resource utilization, liver transplantation and mortality in a large, integrated healthcare system

    NAFLD is the most prevalent liver disease globally, affecting 20% of the world population. Healthcare resource utilization (HRU) attributable to NAFLD has been difficult to define.

    Thomas Gerard Cotter, Li Dong, John Holmen, Richard Gilroy in Journal of Gastroenterology (2020)

  3. No Access

    Chapter

    Introduction

    The recent advent of high precision antihydrogen spectroscopy opens the way to stringent experimental tests on pure antimatter systems of the fundamental principles underlying particle physics and general rela...

    Michael Charlton, Stefan Eriksson, Graham M. Shore in Antihydrogen and Fundamental Physics (2020)

  4. No Access

    Chapter

    Summary and Outlook

    The main themes of the book are summarised, with a critical assessment of the potential of antihydrogen experiments to test the fundamental principles of quantum field theory and general relativity. Future pro...

    Michael Charlton, Stefan Eriksson, Graham M. Shore in Antihydrogen and Fundamental Physics (2020)

  5. No Access

    Chapter

    Other Antimatter Species

    In this chapter, some present and future possibilities for testing fundamental physics principles using antimatter species other than antihydrogen are briefly discussed.

    Michael Charlton, Stefan Eriksson, Graham M. Shore in Antihydrogen and Fundamental Physics (2020)

  6. No Access

    Chapter

    Antihydrogen

    In this chapter, the implications of the ALPHA antihydrogen spectroscopy programme for testing fundamental physical principles are analysed in detail. Explicit calculations are given for the dependence on poss...

    Michael Charlton, Stefan Eriksson, Graham M. Shore in Antihydrogen and Fundamental Physics (2020)

  7. No Access

    Chapter

    Fundamental Principles

    This chapter presents a theoretical review of the role of antiparticles, causality and fundamental symmetries in local relativistic quantum field theory, together with a discussion of the theory of time measur...

    Michael Charlton, Stefan Eriksson, Graham M. Shore in Antihydrogen and Fundamental Physics (2020)

  8. No Access

    Article

    Liver Allocation Policies in the USA: Past, Present, and the Future

    Identifying the optimal allocation policy with regard to hepatocellular carcinoma has been a persistent and evolving challenge. The current criteria for LT for HCC endorsed by the United Network of Organ Shari...

    Anjana Pillai, Thomas Couri, Michael Charlton in Digestive Diseases and Sciences (2019)

  9. No Access

    Article

    Exploring ironmaking practices at Meroe, Sudan—a comparative analysis of archaeological and experimental data

    Recent excavations of a Late to Post-Meroitic furnace workshop at Meroe, Sudan prompted questions concerning the use of some of its unusual design features and the nature of ironmaking practice. To begin addre...

    Michael Charlton, Jane Humphris in Archaeological and Anthropological Sciences (2019)

  10. No Access

    Article

    Surgical Issues in NASH: Bariatric Surgery and Liver Transplantation

    The rising prevalence of obesity in general and non-alcoholic steatohepatitis (NASH) specifically as an indication for liver transplantation has occurred in parallel with an increase in the consideration and p...

    Sonali Paul, Michael Charlton in Current Hepatology Reports (2018)

  11. Article

    Open Access

    Closing in on the properties of antihydrogen

    Recent achievements leading, amongst other things, to the observation of the two-photon 1S–2S transition in antihydrogen are reviewed. We summarise some of the technical advances that were necessary to facili...

    Michael Charlton in The European Physical Journal D (2017)

  12. No Access

    Article

    Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah

    Biliary tract cancers (BTC) including, cholangiocarcinoma (CC) and gallbladder cancer (GBC), are rare and highly fatal malignancies. The etiology and inherited susceptibility of both malignancies are poorly un...

    N. Jewel Samadder, Ken Robert Smith, Jathine Wong in Digestive Diseases and Sciences (2016)

  13. No Access

    Article

    An Update of Liver Transplantation for Nonalcoholic Steatohepatitis

    Nonalcoholic steatohepatitis (NASH), obesity, and the metabolic syndrome are highly prevalent before and after liver transplantation, with NASH currently the second most common indication. This review consider...

    I. Raymond Thomason, Michael Charlton in Current Hepatology Reports (2015)

  14. No Access

    Article

    Progress towards microwave spectroscopy of trapped antihydrogen

    Precision comparisons of hyperfine intervals in atomic hydrogen and antihydrogen are expected to yield experimental tests of the CPT theorem. The CERN-based ALPHA collaboration has initiated a program of study...

    Mohammad D. Ashkezari, Gorm B. Andresen, Marcelo Baquero-Ruiz in Hyperfine Interactions (2012)

  15. No Access

    Article

    Antihydrogen detection in ALPHA

    The ALPHA project is an international collaboration, based at CERN, with the experimental goal of performing precision spectroscopic measurements on antihydrogen. As part of this endeavor, the ALPHA experiment...

    Richard Hydomako, Gorm Bruun Andresen in Hyperfine Interactions (2012)

  16. No Access

    Article

    Compression of positron clouds using rotating wall electric fields

    An asymmetric dipolar rotating electric field can be used to compress a trapped cloud of positrons when applied with a frequency close that of their axial bounce, and in the presence of a low pressure molecula...

    Dirk Peter van der Werf, Christopher Aled Isaac in Hyperfine Interactions (2012)

  17. No Access

    Article

    Genetic Variation in the Peroxisome Proliferator Activated Receptor-Gamma Gene Is Associated with Histologically Advanced NAFLD

    The peroxisome proliferator activated receptor-gamma (PPARG) is a nuclear receptor that regulates adipocyte differentiation, insulin sensitivity and lipid metabolism, thus, it represents a good candidate gene for...

    Samer Gawrieh, Miranda C. Marion, Richard Komorowski in Digestive Diseases and Sciences (2012)

  18. No Access

    Article

    NAFLD and Insulin Resistance Do Not Increase the Risk of Postoperative Complications Among Patients Undergoing Bariatric Surgery—A Prospective Analysis

    Nonalcoholic fatty liver disease (NAFLD) and insulin resistance are common consequences of obesity and are highly prevalent among patients undergoing bariatric surgery. Insulin resistance and NAFLD have been r...

    Tarsila Ribeireiro, James Swain, Michael Sarr, Michael Kendrick in Obesity Surgery (2011)

  19. No Access

    Article

    Hepatic Gene Networks in Morbidly Obese Patients With Nonalcoholic Fatty Liver Disease

    Genetic factors alter the risk for nonalcoholic fatty liver disease (NAFLD). We sought to identify NAFLD-associated genes and elucidate gene networks and pathways involved in the pathogenesis of NAFLD.

    Samer Gawrieh, Tesfaye M. Baye, Melanie Carless, James Wallace in Obesity Surgery (2010)

  20. No Access

    Article

    Approach to recurrent hepatitis C following liver transplantation

    Hepatitis C-associated liver failure is the most common indication for liver transplantation. Histologic evidence of recurrence is apparent in approximately 50% of hepatitis C virus (HCV)-infected recipients i...

    Michael Charlton in Current Gastroenterology Reports (2007)

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