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Article
Open AccessImplementation fidelity to a behavioral diabetes prevention intervention in two New York City safety net primary care practices
It is critical to assess implementation fidelity of evidence-based interventions and factors moderating fidelity, to understand the reasons for their success or failure. However, fidelity and fidelity moderato...
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Article
A simulation model estimates lifetime health and economic outcomes of screening prediabetes using the 1-h plasma glucose
The current method to diagnose impaired glucose tolerance (IGT) is based on the 2-h plasma glucose (2-hPG) value during a 75-g oral glucose tolerance test (OGTT). Robust evidence demonstrates that the 1-h post...
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Article
Continuous glucose monitoring and 1-h plasma glucose identifies glycemic variability and dysglycemia in high-risk individuals with HbA1c < 5.7%: a pilot study
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Article
Remission of T2DM requires early diagnosis and substantial weight reduction
Remission of type 2 diabetes mellitus is highly desirable and potentially reduces risks of complications. Improving the probability of remission requires early detection and substantial weight loss during a 6-...
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Chapter and Conference Paper
Validation of Computational Fluid Dynamics Models for Evaluating Loose-Fitting Powered Air-Purifying Respirators
Loose-fitting powered air-purifying respirators (PAPRs) are used in healthcare settings to reduce exposure to high-risk respiratory pathogens. Innovative computational fluid dynamics (CFD) models were develope...
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Article
Provoceer eens
Sommige cliënten slaan al je zorgvuldig overwogen adviezen in de wind, tonen nauwelijks veranderbereidheid, maar brengen wel psychosociale problemen in en eisen min of meer dat jij de situatie voor hen oplost....
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Article
The 1-h post-load plasma glucose as a novel biomarker for diagnosing dysglycemia
Identifying the earliest moment for intervention to avert progression to prediabetes and diabetes in high-risk individuals is a substantial challenge. As β-cell function is already compromised in prediabetes,...
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Article
Can insulin response patterns predict metabolic disease risk in individuals with normal glucose tolerance? Reply to Crofts CAP, Brookler K, Henderson G [letter]
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Article
Glucose patterns during an oral glucose tolerance test and associations with future diabetes, cardiovascular disease and all-cause mortality rate
In addition to blood glucose concentrations measured in the fasting state and 2 h after an OGTT, intermediate measures during an OGTT may provide additional information regarding a person’s risk of future diab...
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Article
Reducing the prevalence of dysglycemia: is the time ripe to test the effectiveness of intervention in high-risk individuals with elevated 1 h post-load glucose levels?
Identifying the earliest time point on the prediabetic continuum is critical to avoid progressive deterioration in β-cell function. Progressively rising glucose levels even within the “normal range” occur cons...
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Article
The 1-hour post-load glucose level is more effective than HbA1c for screening dysglycemia
To assess the performance of HbA1c and the 1-h plasma glucose (PG ≥ 155 mg/dl; 8.6 mmol/l) in identifying dysglycemia based on the oral glucose tolerance test (OGTT) from a real-world clinical care setting.
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Article
Elevated 1-hour plasma glucose levels are associated with dysglycemia, impaired beta-cell function, and insulin sensitivity: a pilot study from a real world health care setting
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Article
Diabetes as a model for the disparate public response to acute versus chronic diseases
The public health outcry toward infectious entities appears to dwarf chronic diseases such as diabetes. This disparity is particularly astonishing given the considerable prevalence of diabetes and prediabetes....
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Article
Open AccessPreface for the article collection of “Multidisciplinary Researches on Deep Interiors of the Earth and Planets”
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Article
Prediabetes and associated disorders
Prediabetes represents an elevation of plasma glucose above the normal range but below that of clinical diabetes. Prediabetes includes individuals with IFG, IGT, IFG with IGT and elevated HbA1c levels. Insulin...
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Article
Impact of metabolic syndrome on the risk of atrial fibrillation recurrence after catheter ablation: systematic review and meta-analysis
The impact of metabolic syndrome (MetS) on recurrence of atrial fibrillation (AF) after catheter ablation remains uncertain. We conducted a meta-analysis to summarize the relative risks (RR) of AF recurrence a...
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Article
Inadequacies of current approaches to prediabetes and diabetes prevention
In view of the global shift from communicable to chronic, non-communicable diseases including obesity, prediabetes, and type 2 diabetes mellitus, the increasing prevalence of the latter creates a considerable ...
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Article
Are current diagnostic guidelines delaying early detection of dysglycemic states? Time for new approaches
Diagnosis of dysglycemic states is likely delayed as current diagnostic criteria apply absolute threshold values to a process that is continuous. The importance of this relates to forestalling opportunities fo...
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Article
Pathophysiology of prediabetes and treatment implications for the prevention of type 2 diabetes mellitus
Type 2 diabetes and other non-communicable diseases (NCD) are a growing public health challenge globally. An estimated 285 million people, corresponding to 6.4 % of the world’s adult population has diabetes. T...
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Article
Calcium Nephrolithiasis
Nephrolithiasis is a major cause of morbidity involving the urinary tract. The prevalence of this disease in the United States increased from 3.8% in the 1970s to 5.2% in the 1990s. There were nearly 2 million...