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  1. No Access

    Article

    Remission of T2DM requires early diagnosis and substantial weight reduction

    Remission of type 2 diabetes mellitus is highly desirable and potentially reduces risks of complications. Improving the probability of remission requires early detection and substantial weight loss during a 6-...

    Michael Bergman, Martin Buysschaert, José Luiz Medina… in Nature Reviews Endocrinology (2022)

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    Article

    The 1-h post-load plasma glucose as a novel biomarker for diagnosing dysglycemia

    Identifying the earliest moment for intervention to avert progression to prediabetes and diabetes in high-risk individuals is a substantial challenge. As β-cell function is already compromised in prediabetes,...

    Ram Jagannathan, Martin Buysschaert, José Luis Medina, Karin Katz… in Acta Diabetologica (2018)

  3. No Access

    Article

    Reducing the prevalence of dysglycemia: is the time ripe to test the effectiveness of intervention in high-risk individuals with elevated 1 h post-load glucose levels?

    Identifying the earliest time point on the prediabetic continuum is critical to avoid progressive deterioration in β-cell function. Progressively rising glucose levels even within the “normal range” occur cons...

    Michael Bergman, Ram Jagannathan, Martin Buysschaert, Jose Luis Medina… in Endocrine (2017)

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    Article

    The 1-hour post-load glucose level is more effective than HbA1c for screening dysglycemia

    To assess the performance of HbA1c and the 1-h plasma glucose (PG ≥ 155 mg/dl; 8.6 mmol/l) in identifying dysglycemia based on the oral glucose tolerance test (OGTT) from a real-world clinical care setting.

    Ram Jagannathan, Mary Ann Sevick, Dorothy Fink, Rachel Dankner… in Acta Diabetologica (2016)

  5. No Access

    Article

    Prediabetes and associated disorders

    Prediabetes represents an elevation of plasma glucose above the normal range but below that of clinical diabetes. Prediabetes includes individuals with IFG, IGT, IFG with IGT and elevated HbA1c levels. Insulin...

    Martin Buysschaert, José Luís Medina, Michael Bergman, Avni Shah… in Endocrine (2015)

  6. No Access

    Article

    What are the characteristics of phenotypic type 2 diabetic patients with low-titer GAD65 antibodies?

    Type 2 diabetes results from combined insulin resistance and β-cell deficiency. Type 1 diabetes results from β-cell destruction associated with islet autoantibodies, including those directed against glutamate ...

    Yovan P. Mahadeb, Damien Gruson, Martin Buysschaert… in Acta Diabetologica (2014)

  7. No Access

    Article

    Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes

    Cytochrome P4502E1 (CYP2E1) is expressed in human peripheral blood lymphocytes (PBLs), and previous reports have suggested the possibility of using this readily available tissue as a reporter of CYP2E1 status....

    Vincent Haufroid, Danuta Ligocka… in European Journal of Clinical Pharmacology (2003)

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    Article

    Alcoholic liver disease: Value of the left-to-right portal vein ratio in its sonographic diagnosis

    A study group of 50 patients in whom the left portal vein diameter was equal to or greater than the right portal vein diameter (LPVD≥RPVD) was prospectively compared on ultrasonography with a control group of ...

    Jean Paul Trigaux M.D., Bernard Van Beers, Michel Melange… in Gastrointestinal Radiology (1991)