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    Isoform-Selective Assays for Sphingosine Kinase Activity

    Sphingosine kinases (SK) 1 and 2 are unique lipid kinases that phosphorylate sphingosine to form ­sphingosine-1-phosphate (S1P). S1P is a bioactive molecule eliciting multiple effects both extracellularly via ...

    Melissa R. Pitman, Duyen H. Pham, Stuart M. Pitson in Sphingosine-1-Phosphate (2012)