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Article
Canada’s approach to SARS-CoV-2 sero-surveillance: Lessons learned for routine surveillance and future pandemics
In Canada’s federated healthcare system, 13 provincial and territorial jurisdictions have independent responsibility to collect data to inform health policies. During the COVID-19 pandemic (2020–2023), nationa...
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Article
Open AccessExpanding access to healthcare for people who use drugs and sex workers: hepatitis C elimination implications from a qualitative study of healthcare experiences in British Columbia, Canada
Hepatitis C virus (HCV) is a major health threat in Canada. In British Columbia (BC) province, 1.6% of the population had been exposed to HCV by 2012. Prevalence and incidence of HCV are very high in populatio...
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Article
Open AccessFactors associated with SARS-CoV-2 infection in unvaccinated children and young adults
Pediatric COVID-19 cases are often mild or asymptomatic, which has complicated estimations of disease burden using existing testing practices. We aimed to determine the age-specific population seropositivity a...
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Article
Open AccessWomen in the 2019 hepatitis C cascade of care: findings from the British Columbia Hepatitis Testers cohort study
Women living with hepatitis C virus (HCV) are rarely addressed in research and may be overrepresented within key populations requiring additional support to access HCV care and treatment. We constructed the H...
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Article
The Impact of Treatment as Prevention on the HIV Epidemic in British Columbia, Canada
This study proposes to describe the impact of a publicly funded Treatment as Prevention (TasP) strategy in British Columbia (BC), Canada, in decreasing the individual and public health impact of the HIV/AIDS E...
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Article
Open AccessTreatment outcomes for isoniazid-resistant tuberculosis under program conditions in British Columbia, Canada
Every year, over 1 million people develop isoniazid (INH) resistant tuberculosis (TB). Yet, the optimal treatment regimen remains unclear. Given increasing prevalence, the clinical efficacy of regimens used by...
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Article
Open AccessTwin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepatitis Testers Cohort
We characterized the twin epidemics of new and prevalent hepatitis C virus (HCV) infections in British Columbia, Canada to inform prevention, care and treatment programs.
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Article
Open AccessWomen’s intentions to self-collect samples for human papillomavirus testing in an organized cervical cancer screening program
Mounting evidence affirms HPV testing as an effective cervical cancer screening tool, and many organized screening programs are considering adopting it as primary testing. HPV self-collection has comparable se...
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Article
Open AccessSelf-collected versus clinician-collected sampling for sexually transmitted infections: a systematic review and meta-analysis protocol
Three meta-analyses and one systematic review have been conducted on the question of whether self-collected specimens are as accurate as clinician-collected specimens for STI screening. However, these reviews ...
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Article
Open AccessMortality among British Columbians testing for hepatitis C antibody
Hepatitis C virus (HCV) infection is a major preventable and treatable cause of morbidity and mortality. The ability to link population based centralized laboratory HCV testing data with administrative databas...
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Article
Open AccessTowards targeted screening for acute HIV infections in British Columbia
Our objective was to describe the characteristics of acute and established HIV infections diagnosed in the Canadian province of British Columbia. Province-wide HIV testing and surveillance data were analyzed t...
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Article
Open AccessHCV co-infection in HIV positive population in British Columbia, Canada
As HIV and hepatitis C (HCV) share some modes of transmission co-infection is not uncommon. This study used a population-based sample of HIV and HCV tested individuals to determine the prevalence of HIV/HCV co...
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Protocol
Hepatitis B Virus
Hepatitis B virus (HBV) is a member of the Hepadnaviridae family and has a (3200-bp) partially double-stranded circular DNA genome (1). This virus causes subclinical, acute self-limited, chronic, and fulminant he...