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    Article

    Canada’s approach to SARS-CoV-2 sero-surveillance: Lessons learned for routine surveillance and future pandemics

    In Canada’s federated healthcare system, 13 provincial and territorial jurisdictions have independent responsibility to collect data to inform health policies. During the COVID-19 pandemic (2020–2023), nationa...

    Sheila F. O’Brien, Michael Asamoah-Boaheng in Canadian Journal of Public Health (2024)

  2. Article

    Open Access

    Expanding access to healthcare for people who use drugs and sex workers: hepatitis C elimination implications from a qualitative study of healthcare experiences in British Columbia, Canada

    Hepatitis C virus (HCV) is a major health threat in Canada. In British Columbia (BC) province, 1.6% of the population had been exposed to HCV by 2012. Prevalence and incidence of HCV are very high in populatio...

    Nance E. Cunningham, Jessica Lamb, Amanda Staller, Mel Krajden in Harm Reduction Journal (2024)

  3. Article

    Open Access

    Factors associated with SARS-CoV-2 infection in unvaccinated children and young adults

    Pediatric COVID-19 cases are often mild or asymptomatic, which has complicated estimations of disease burden using existing testing practices. We aimed to determine the age-specific population seropositivity a...

    Sarah L. Silverberg, Hennady P. Shulha, Brynn McMillan in BMC Infectious Diseases (2024)

  4. Article

    Open Access

    Women in the 2019 hepatitis C cascade of care: findings from the British Columbia Hepatitis Testers cohort study

    Women living with hepatitis C virus (HCV) are rarely addressed in research and may be overrepresented within key populations requiring additional support to access HCV care and treatment. We constructed the H...

    Margo E. Pearce, Sofia R. Bartlett, Amanda Yu, Jess Lamb in BMC Women's Health (2021)

  5. No Access

    Article

    The Impact of Treatment as Prevention on the HIV Epidemic in British Columbia, Canada

    This study proposes to describe the impact of a publicly funded Treatment as Prevention (TasP) strategy in British Columbia (BC), Canada, in decreasing the individual and public health impact of the HIV/AIDS E...

    Viviane D. Lima, Zabrina L. Brumme, Chanson Brumme, Paul Sereda in Current HIV/AIDS Reports (2020)

  6. Article

    Open Access

    Treatment outcomes for isoniazid-resistant tuberculosis under program conditions in British Columbia, Canada

    Every year, over 1 million people develop isoniazid (INH) resistant tuberculosis (TB). Yet, the optimal treatment regimen remains unclear. Given increasing prevalence, the clinical efficacy of regimens used by...

    Kamila Romanowski, Leslie Y. Chiang, David Z. Roth, Mel Krajden in BMC Infectious Diseases (2017)

  7. Article

    Open Access

    Twin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepatitis Testers Cohort

    We characterized the twin epidemics of new and prevalent hepatitis C virus (HCV) infections in British Columbia, Canada to inform prevention, care and treatment programs.

    Naveed Zafar Janjua, Amanda Yu, Margot Kuo, Maria Alvarez in BMC Infectious Diseases (2016)

  8. Article

    Open Access

    Women’s intentions to self-collect samples for human papillomavirus testing in an organized cervical cancer screening program

    Mounting evidence affirms HPV testing as an effective cervical cancer screening tool, and many organized screening programs are considering adopting it as primary testing. HPV self-collection has comparable se...

    Laurie W Smith, Fareeza Khurshed, Dirk J van Niekerk, Mel Krajden in BMC Public Health (2014)

  9. Article

    Open Access

    Self-collected versus clinician-collected sampling for sexually transmitted infections: a systematic review and meta-analysis protocol

    Three meta-analyses and one systematic review have been conducted on the question of whether self-collected specimens are as accurate as clinician-collected specimens for STI screening. However, these reviews ...

    Darlene Taylor, Carole Lunny, Tom Wong, Mark Gilbert, Neville Li in Systematic Reviews (2013)

  10. Article

    Open Access

    Mortality among British Columbians testing for hepatitis C antibody

    Hepatitis C virus (HCV) infection is a major preventable and treatable cause of morbidity and mortality. The ability to link population based centralized laboratory HCV testing data with administrative databas...

    Amanda Yu, John J Spinelli, Darrel A Cook, Jane A Buxton, Mel Krajden in BMC Public Health (2013)

  11. Article

    Open Access

    Towards targeted screening for acute HIV infections in British Columbia

    Our objective was to describe the characteristics of acute and established HIV infections diagnosed in the Canadian province of British Columbia. Province-wide HIV testing and surveillance data were analyzed t...

    Malcolm Steinberg, Darrel A Cook, Mark Gilbert in Journal of the International AIDS Society (2011)

  12. Article

    Open Access

    HCV co-infection in HIV positive population in British Columbia, Canada

    As HIV and hepatitis C (HCV) share some modes of transmission co-infection is not uncommon. This study used a population-based sample of HIV and HCV tested individuals to determine the prevalence of HIV/HCV co...

    Jane A Buxton, Amanda Yu, Paul H Kim, John J Spinelli, Margot Kuo in BMC Public Health (2010)

  13. No Access

    Protocol

    Hepatitis B Virus

    Hepatitis B virus (HBV) is a member of the Hepadnaviridae family and has a (3200-bp) partially double-stranded circular DNA genome (1). This virus causes subclinical, acute self-limited, chronic, and fulminant he...

    Mel Krajden in Sexually Transmitted Diseases (1999)