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Article
Prediction of cognitive decline in healthy aging based on neuropsychiatric symptoms and PET-biomarkers of Alzheimer's disease
Neuropsychiatric symptoms (NPS) have been associated with a risk of accelerated cognitive decline or conversion to dementia of the Alzheimer’s Disease (AD) type. Moreover, the NPS were also associated with hig...
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Article
Open AccessAuthor Correction: In vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men
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Article
Open AccessIn vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men
The regional integrity of brain subcortical structures has been implicated in sleep–wake regulation, however, their associations with sleep parameters remain largely unexplored. Here, we assessed association b...
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Article
Open AccessUltra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau
Autopsy data indicate that the locus coeruleus (LC) is one of the first sites in the brain to accumulate hyperphosphorylated tau pathology, with the rostral part possibly being more vulnerable in the earlier s...
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Article
Open AccessAssociations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer’s disease plasma biomarkers: a 7T MRI study
The brainstem locus coeruleus (LC) constitutes the intersection of the initial pathophysiological processes of Alzheimer’s disease (AD) and sleep-wake dysregulation in the preclinical stages of the disease. Ho...
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Article
Open AccessAuthor Correction: Preserved wake-dependent cortical excitability dynamics predict cognitive fitness beyond age-related brain alterations
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01995-5
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Article
Open AccessPreserved wake-dependent cortical excitability dynamics predict cognitive fitness beyond age-related brain alterations
Age-related cognitive decline arises from alterations in brain structure as well as in sleep-wake regulation. Here, we investigated whether preserved wake-dependent regulation of cortical function could repres...
