-
Article
A sentinel function for teat tissues in dairy cows: dominant innate immune response elements define early response to E. coli mastitis
Escherichia coli intramammary infection elicits localized and systemic responses, some of which have been characterized in mammary secretory tissue. Our objective was to characterize gene expression patterns that...
-
Article
Correction: Corrigendum: Genetically enhanced cows resist intramammary Staphylococcus aureus infection
Nat. Biotechnol. 23, 445–451 (2005) In the abstract on page 445, the quantities given for lysostaphin in the following sentences are incorrect: “To test the feasibility of protecting animals through genetic en...
-
Article
Genetically enhanced cows resist intramammary Staphylococcus aureus infection
Mastitis, the most consequential disease in dairy cattle, costs the US dairy industry billions of dollars annually. To test the feasibility of protecting animals through genetic engineering, transgenic cows se...
-
Chapter
Immune Surveillance of Mammary Tissue by Phagocytic Cells
The leukocytes in milk consist of lymphocytes, neutrophil polymorphonuclear leukocytes (PMN) and macrophages. Lymphocytes together with antigen- presenting cells function in the generation of an effective immu...
-
Article
Continuous culture of pig tissue-derived macrophages
Normal tissue macrophages from fetal and adult pig tissues can be continuously cultured by growing simple explant cultures on feeder layers of STO mouse embryonic fibroblasts. Macrophage cultures initiated fro...
-
Article
Continuous cultures of macrophages derived from the 8-day epiblast of the pig
Secondary macrophage cell cultures were generated from the primary culture of epiblasts of 8-d-old pig blastocysts. The epiblast-derived macrophagelike (EDM) cells have a morphology and ameboid behavior that i...
