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Article
Open AccessNature of bacterial colonization influences transcription of mucin genes in mice during the first week of life
Postnatal regulation of the small intestinal mucus layer is potentially important in the development of adult gut functionality. We hypothesized that the nature of bacterial colonization affects mucus gene reg...
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Article
A pre-processing strategy for liquid chromatography time-of-flight mass spectrometry metabolic fingerprinting data
A series of simple and robust operations for handling large chromatographic time-of-flight mass spectrometry fingerprinting data has been established and applied to data from extracts of Fusarium graminearum geno...
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Article
Open AccessLactobacillus acidophilus induces a slow but more sustained chemokine and cytokine response in naïve foetal enterocytes compared to commensal Escherichia coli
The first exposure to microorganisms at mucosal surfaces is critical for immune maturation and gut health. Facultative anaerobic bacteria are the first to colonise the infant gut, and the impact of these bacte...
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Article
Open AccessEfficient four fragment cloning for the construction of vectors for targeted gene replacement in filamentous fungi
The rapid increase in whole genome fungal sequence information allows large scale functional analyses of target genes. Efficient transformation methods to obtain site-directed gene replacement, targeted over-e...