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Open AccessRNA recovery from specimens of duct-washing cytology performed contemporaneously with mammary ductoscopy
Conventional cytological diagnosis including duct-washing cytology (DWC) is sometimes performed using ductal epithelial cells collected during mammary ductoscopy; it is useful for detection of early-stage brea...
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Open AccessMicroarray analysis of ductal carcinoma in situ samples obtained by puncture from surgical resection specimens
The incidence of ductal carcinoma in situ (DCIS) is increasing due to more widespread mammographic screening. DCIS, the earliest form of breast cancer, is non-invasive at the time of detection. If DCIS tissues...
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Open AccessMoving a neodymium magnet promotes the migration of a magnetic tracer and increases the monitoring counts on the skin surface of sentinel lymph nodes in breast cancer
We suspected that moving a small neodymium magnet would promote migration of the magnetic tracer to the sentinel lymph node (SLN). Higher monitoring counts on the skin surface before making an incision help us...
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Characteristics of adverse events of endocrine therapies among older patients with breast cancer
To clarify the profile of adverse events from endocrine therapies in older patients.
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Long-term prognoses and outcomes of axillary lymph node recurrence in 2,578 sentinel lymph node-negative patients for whom axillary lymph node dissection was omitted: results from one Japanese hospital
Axillary dissection omission for sentinel lymph node-negative patients has been a practice at Cancer Institute Hospital, Japanese Foundation for Cancer Research since 2003. We examined the long-term results of...
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Optimal surveillance for postoperative metastasis in breast cancer patients
To establish an optimal surveillance schedule after surgery for breast cancer, patients included in an institutional database were retrospectively investigated with respect to the first metastatic site and tim...
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Mammary ductoscopy and watchful follow-up substitute microdochectomy in patients with bloody nipple discharge
In order to evaluate the diagnostic and therapeutic potential of mammary ductoscopy and watchful follow-up for treating bloody nipple discharge, we investigated the incidence of cancer evolving from the locati...
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Open AccessDecreased hormonal sensitivity after childbirth rather than the tumor size influences the prognosis of very young breast cancer patients
There is a significant difference in the mean tumor size between very young breast cancer patients and their elder counterparts. A simple comparison may show obvious prognostic differences. We investigated the...
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Validation study of the UICC TNM classification of malignant tumors, seventh edition, in breast cancer
The TNM classification of the Unio Internationalis Contra Cancrum was revised for the seventh edition. The major change concerning breast cancer is a change in the stages for patients with T0 or T1N1miM0. In t...
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Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors
Malignant phyllodes tumor of the breast is a rare neoplasm for which clinical findings remain insufficient for determination of optimal management. We examined the clinical behavior of these lesions in an atte...
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Open AccessDuctal carcinoma in situ and sentinel lymph node metastasis in breast cancer
The impact of sentinel lymph node biopsy on breast cancer mimicking ductal carcinoma in situ (DCIS) is a matter of debate.
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Favourable long-term results after surgical removal of lung metastases of breast cancer
We retrospectively evaluated whether a surgical strategy benefits patients with operable lung metastasis of breast cancer. Between 1960 and 2000, 90 patients (mean age 55.1; range 32–77) with lung metastasis (...
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Open AccessSkin invasion and prognosis in node negative breast cancer: a retrospective study
The impact of skin invasion in node negative breast cancer is uncertain.
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Diagnostic mammography and ultrasonography for palpable and nonpalpable breast cancer in women aged 30 to 39 years
Purpose: To investigate the relationship between the tumor size of breast cancer by palpation and the sensitivity of mammography (MMG) and ultrasonography (US), and which modality can detect nonpalpable breast...
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diagnostic ultrasonography and mammography for invasive and noninvasive breast cancer in women aged 30 to 39 years
To confirm which modality, ultrasonography (US) or mammography (MMG), is useful to detect breast cancer in women aged 30 to 39 years, and to compare the sensitivity and findings of these two modalities for inv...
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Tolerability and safety of classic cyclophosphamide, methotrexate, and fluorouracil treatment in japanese patients with early Breast Cancer
Few reports have addressed the feasibility and safety of classic Cyclophosphamide, Methotrexate, and Fluorouracil (CMF) therapy in Japanese female breast cancer patients.
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Open AccessFrozen section is superior to imprint cytology for the intra-operative assessment of sentinel lymph node metastasis in Stage I Breast cancer patients
A standard intra-operative procedure for assessing sentinel lymph node metastasis in breast cancer patients has not yet been established.
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Intraductal papilloma with bloody discharge from montgomery’s areolar tubercle examined by ductoscopy from the areola
A patient with intraductal papilloma who had abnormal bloody discharge from Montgomery’s areolar tubercle underwent mammary ductography, mammary ductoscopy from the tubercle, and microdochectomy.
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Postoperative prognosis of node-negative breast cancers predicted by gene-expression profiling on a cDNA microarray of 25,344 genes
In Japan, postoperative relapse occurs within five years in 9.2 to 16% of patients whose breast cancers have not metastasized to lymph nodes at the time of initial surgery (node-negative, n0). Attempts to find...
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Classification of ipsilateral breast tumor recurrence after breast-conserving therapy: New primary cancer allows a good prognosis
To classify and assess ipsilateral breast tumor recurrences (IBTR) after breast-conserving therapy.