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  1. Article

    Open Access

    Co** with time scales in disease systems analysis: application to bone remodeling

    In this study we demonstrate the added value of mathematical model reduction for characterizing complex dynamic systems using bone remodeling as an example. We show that for the given parameter values, the mec...

    Stephan Schmidt, Teun M. Post… in Journal of Pharmacokinetics and Pharmacody… (2011)

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  2. No Access

    Chapter

    Disease Progression Analysis: Towards Mechanism-Based Models

    Sustained disturbances of the biological homeostasis can result in chronic progressive diseases. The respective disease status as well as the corresponding effect of drug treatment on disease progression can b...

    Stephan Schmidt, Teun M. Post, Massoud A. Boroujerdi… in Clinical Trial Simulations (2011)