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Open AccessDevelopment of fibrocartilage layers in the anterior cruciate ligament insertion in rabbits
A detailed evaluation focusing on the fibrocartilage layers in the anterior cruciate ligament (ACL) insertion is necessary to consider regeneration of the insertion. This study examined the development of the ...
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Article
Open AccessAnatomic single-bundle anterior cruciate ligament reconstruction using a calcium phosphate-hybridized tendon graft: a randomized controlled trial with 2 years of follow-up
To improve tendon-to-bone healing in anterior cruciate ligament (ACL) reconstruction, a novel technique via calcium phosphate (CaP)-hybridized tendon graft using an alternate soaking process was developed. The...
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Article
Calcium phosphate-hybridized tendon grafts reduce femoral bone tunnel enlargement in anatomic single-bundle ACL reconstruction
This study aimed to clarify the effect of calcium phosphate (CaP)-hybridized tendon grafting versus unhybridized tendon grafting on the morphological changes to the bone tunnels at the aperture 1 year after an...
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Article
Open AccessDifferences in placement of calcium phosphate-hybridized tendon grafts within the femoral bone tunnel during ACL reconstruction do not influence tendon-to-bone healing
Calcium phosphate (CaP)-hybridization of tendon grafts has been shown to improve tendon-to-bone healing. The purpose of this study was to clarify the influence of different tendon graft placement methods on te...
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Article
Open AccessNovel unidirectional porous hydroxyapatite used as a bone substitute for open wedge high tibial osteotomy
Purpose: The purpose of this study was to clinically and radiologically evaluate the availability, osteoconductivity, and resorption of a novel unidirectional porous hydroxyapatite (UDPHAp) used as an artifici...
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Article
Open AccessPilot study of locomotion improvement using hybrid assistive limb in chronic stroke patients
Locomotor training using robots is increasingly being used for rehabilitation to reduce manpower and the heavy burden on therapists, and the effectiveness of such techniques has been investigated. The robot su...
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Article
The effects of plasma rich in growth factors (PRGF-Endoret) on healing of medial collateral ligament of the knee
Platelet-rich plasma (PRP) has been increasingly used in sports-related injuries for therapeutic applications. However, there are numerous manufacturing procedures and treatment protocols of PRP use, which mak...
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Article
Enhanced wound healing associated with Sharpey’s fiber-like tissue formation around FGF-2-apatite composite layers on percutaneous titanium screws in rabbits
Pin-tract infections are the most common complications of external fixation. To solve the problem, we developed a fibroblast growth factor-2 (FGF-2)-apatite composite layer for coating titanium screws. The pur...
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Article
Anterior cruciate ligament insertion after partial tear: histological changes and chondrocyte turnover
The purpose of this study was to clarify the effects of partial resection on the glycosaminoglycan (GAG) layer thicknesses and chondrocyte turnover (apoptosis and cell proliferation) between uncalcified fibroc...
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Article
Open AccessCalcium phosphate-hybridized tendon graft to enhance tendon-bone healing two years after ACL reconstruction in goats
We developed a novel technique to improve tendon-bone attachment by hybridizing calcium phosphate (CaP) with a tendon graft using an alternate soaking process. However, the long-term result with regard to the ...
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Article
Multiple capillary hemangiomas of the cauda equina at a level of a single vertebra
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Open AccessTime dependence of changes of two cartilage layers in anterior cruciate ligament insertion after resection on chondrocyte apoptosis and decrease in glycosaminoglycan
The purpose of this study is to clarify the differences in time-dependent histological changes (chondrocyte apoptosis and glycosaminoglycan (GAG) layer thickness decrease) between uncalcified fibrocartilage (U...
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Article
Calcium phosphate coating formed in infusion fluid mixture to enhance fixation strength of titanium screws
A novel technique was developed to coat a calcium phosphate (CaP) layer on titanium screws with a titanium oxide surface layer, using infusion fluids officially approved for clinical use. A calcium-containing ...
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Article
Extraskeletal mesenchymal chondrosarcoma of the cervical meninx
We report a case of recurrent mesenchymal chondrosarcoma in the cervical paravertebral region that was diagnosed preoperatively by imaging studies. The tumor showed findings of a well-differentiated cartilagin...
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Article
Histological changes and apoptosis of cartilage layer in human anterior cruciate ligament tibial insertion after rupture
The purpose of this study is to investigate the histological changes and apoptosis of cartilaginous layers in human anterior cruciate ligament (ACL) tibial insertion at different time periods after rupture. By...
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Article
In-situ force in the medial and lateral structures of intact and ACL-deficient knees
The anterior cruciate ligament (ACL) is the major contributor to limit excessive anterior tibial translation (ATT) when the knee is subjected to an anterior tibial load. However, the importance of the medial ...
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Article
Relative contribution of the ACL, MCL, and bony contact to the anterior stability of the knee
Ligaments and other soft tissues, as well as bony contact, all contribute to anterior stability of the knee joint. This study was designed to measure the in situ force in the medial collateral ligament (MCL),...
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Article
The contribution of the anterior cruciate ligament to knee joint kinematics: Evaluation of its in situ forces using a robot/universal force-moment sensor test system
Damage to one of the major soft tissue structures of the knee joint, namely, the anterior cruciate ligament (ACL), can lead to significant changes in joint kinematics, which the patient perceives as instabilit...
