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  1. No Access

    Article

    Safety of terminally gamma-ray-sterilized screws coated with fibroblast growth factor 2-calcium phosphate composite layers in non-human primates

    Screws coated with fibroblast growth factor 2 (FGF-2)-calcium phosphate (CP) composite layers exhibit enhanced soft tissue and bone formation and angiogenesis because of the biological activity of FGF-2. Furth...

    Yukei Matsumoto, Hirotaka Mutsuzaki, Katsuya Nagashima in Journal of Artificial Organs (2023)

  2. Article

    Open Access

    Evaluation of hand functions and distal radioulnar joint instability in elite wheelchair basketball athletes: a cross-sectional pilot study

    Wrist injury affects wheelchair basketball players’ performance; however, the relationship between distal radioulnar joint (DRUJ) instability and hand functions is unclear. This cross-sectional pilot study inv...

    Hiroshi Yuine, Hirotaka Mutsuzaki in BMC Sports Science, Medicine and Rehabilit… (2023)

  3. Article

    Open Access

    Characteristic MRI findings of the shoulder, elbow, and wrist joints in elite wheelchair basketball players

    The health of wheelchair users’ upper limbs is directly related to their quality of life. Moreover, para-sport athletes are subjected to a dual load on their upper extremities from competition and daily life, ...

    Masafumi Sakai, Hirotaka Mutsuzaki in BMC Sports Science, Medicine and Rehabilit… (2022)

  4. Article

    Correction to: Characteristic MRI findings of shoulder, elbow, and wrist joints in wheelchair user

    A correction to this paper has been published: https://doi.org/10.1007/s00256-021-03717-8

    Masafumi Sakai, Hirotaka Mutsuzaki, Yukiyo Shimizu, Yoshikazu Okamoto in Skeletal Radiology (2021)

  5. Article

    Open Access

    Development of fibrocartilage layers in the anterior cruciate ligament insertion in rabbits

    A detailed evaluation focusing on the fibrocartilage layers in the anterior cruciate ligament (ACL) insertion is necessary to consider regeneration of the insertion. This study examined the development of the ...

    Hirotaka Mutsuzaki, Hiromi Nakajima, Maika Someji in BMC Musculoskeletal Disorders (2019)

  6. Article

    Open Access

    Anatomic single-bundle anterior cruciate ligament reconstruction using a calcium phosphate-hybridized tendon graft: a randomized controlled trial with 2 years of follow-up

    To improve tendon-to-bone healing in anterior cruciate ligament (ACL) reconstruction, a novel technique via calcium phosphate (CaP)-hybridized tendon graft using an alternate soaking process was developed. The...

    Hirotaka Mutsuzaki, Tomonori Kinugasa in Journal of Orthopaedic Surgery and Research (2018)

  7. Article

    Open Access

    Training with Hybrid Assistive Limb for walking function after total knee arthroplasty

    The Hybrid Assistive Limb (HAL, CYBERDYNE) is a wearable robot that provides assistance to patients while walking, standing, and performing leg movements based on the intended movement of the wearer. We aimed ...

    Kenichi Yoshikawa, Hirotaka Mutsuzaki in Journal of Orthopaedic Surgery and Research (2018)

  8. Article

    Open Access

    Use of Hybrid Assistive Limb (HAL®) for a postoperative patient with cerebral palsy: a case report

    The Hybrid Assistive Limb (HAL®) is an exoskeleton wearable robot suit that assists in voluntary control of knee and hip joint motion. There have been several studies on HAL intervention effects in stroke, spinal...

    Yuki Mataki, Hiroshi Kamada, Hirotaka Mutsuzaki, Yukiyo Shimizu in BMC Research Notes (2018)

  9. No Access

    Article

    Calcium phosphate-hybridized tendon grafts reduce femoral bone tunnel enlargement in anatomic single-bundle ACL reconstruction

    This study aimed to clarify the effect of calcium phosphate (CaP)-hybridized tendon grafting versus unhybridized tendon grafting on the morphological changes to the bone tunnels at the aperture 1 year after an...

    Hirotaka Mutsuzaki, Tomonori Kinugasa in Knee Surgery, Sports Traumatology, Arthros… (2018)

  10. Article

    Open Access

    Investigation of perioperative safety and clinical results of one-stage bilateral total knee arthroplasty in selected low-risk patients

    An increased perioperative complication rate has been a concern with one-stage bilateral total knee arthroplasty (TKA). The purpose of this study was to retrospectively investigate the perioperative safety and...

    Hirotaka Mutsuzaki, Arata Watanabe in Journal of Orthopaedic Surgery and Research (2018)

  11. Article

    Open Access

    Differences in placement of calcium phosphate-hybridized tendon grafts within the femoral bone tunnel during ACL reconstruction do not influence tendon-to-bone healing

    Calcium phosphate (CaP)-hybridization of tendon grafts has been shown to improve tendon-to-bone healing. The purpose of this study was to clarify the influence of different tendon graft placement methods on te...

    Hirotaka Mutsuzaki, Hiromi Nakajima in Journal of Orthopaedic Surgery and Research (2017)

  12. Article

    Open Access

    Reducing the risk of impaired bone apposition to titanium screws with the use of fibroblast growth factor-2−apatite composite layer coating

    Loosening of screws is a common problem in orthopedic and maxillofacial surgery. Modifying the implant surface to improve the mechanical strength of screws has been tried and reported. We developed screws coat...

    Kengo Fujii, Atsuo Ito, Hirotaka Mutsuzaki in Journal of Orthopaedic Surgery and Research (2017)

  13. Article

    Open Access

    Simple method for confirming tibial osteotomy during total knee arthroplasty

    Achieving precise implant alignment is crucial for producing good outcomes after total knee arthroplasty (TKA). We introduce a simple method for confirming the accuracy of tibial osteotomy during TKA.

    Hirotaka Mutsuzaki, Kotaro Ikeda in Sports Medicine, Arthroscopy, Rehabilitati… (2012)

  14. Article

    Open Access

    Intra-articular injection of tranexamic acid via a drain plus drain-clam** to reduce blood loss in cementless total knee arthroplasty

    Patients undergoing cementless total knee arthroplasty (TKA) sometimes suffer large blood loss. In a retrospective study, we explored whether postoperative intra-articular retrograde injection of tranexamic ac...

    Hirotaka Mutsuzaki, Kotaro Ikeda in Journal of Orthopaedic Surgery and Research (2012)

  15. No Access

    Article

    Enhanced wound healing associated with Sharpey’s fiber-like tissue formation around FGF-2-apatite composite layers on percutaneous titanium screws in rabbits

    Pin-tract infections are the most common complications of external fixation. To solve the problem, we developed a fibroblast growth factor-2 (FGF-2)-apatite composite layer for coating titanium screws. The pur...

    Hirotaka Mutsuzaki, Atsuo Ito, Yu Sogo in Archives of Orthopaedic and Trauma Surgery (2012)

  16. No Access

    Article

    Anterior cruciate ligament insertion after partial tear: histological changes and chondrocyte turnover

    The purpose of this study was to clarify the effects of partial resection on the glycosaminoglycan (GAG) layer thicknesses and chondrocyte turnover (apoptosis and cell proliferation) between uncalcified fibroc...

    Masataka Sakane, Hirotaka Mutsuzaki in Knee Surgery, Sports Traumatology, Arthros… (2012)

  17. Article

    Open Access

    Calcium phosphate-hybridized tendon graft to enhance tendon-bone healing two years after ACL reconstruction in goats

    We developed a novel technique to improve tendon-bone attachment by hybridizing calcium phosphate (CaP) with a tendon graft using an alternate soaking process. However, the long-term result with regard to the ...

    Hirotaka Mutsuzaki, Masataka Sakane in Sports Medicine, Arthroscopy, Rehabilitati… (2011)

  18. Article

    Open Access

    Time dependence of changes of two cartilage layers in anterior cruciate ligament insertion after resection on chondrocyte apoptosis and decrease in glycosaminoglycan

    The purpose of this study is to clarify the differences in time-dependent histological changes (chondrocyte apoptosis and glycosaminoglycan (GAG) layer thickness decrease) between uncalcified fibrocartilage (U...

    Masataka Sakane, Hirotaka Mutsuzaki in BMC Sports Science, Medicine and Rehabilit… (2009)

  19. No Access

    Article

    Calcium phosphate coating formed in infusion fluid mixture to enhance fixation strength of titanium screws

    A novel technique was developed to coat a calcium phosphate (CaP) layer on titanium screws with a titanium oxide surface layer, using infusion fluids officially approved for clinical use. A calcium-containing ...

    Hirotaka Mutsuzaki, Atsuo Ito in Journal of Materials Science: Materials in… (2007)

  20. No Access

    Article

    Histological changes and apoptosis of cartilage layer in human anterior cruciate ligament tibial insertion after rupture

    The purpose of this study is to investigate the histological changes and apoptosis of cartilaginous layers in human anterior cruciate ligament (ACL) tibial insertion at different time periods after rupture. By...

    Hirotaka Mutsuzaki, Masataka Sakane in Knee Surgery, Sports Traumatology, Arthros… (2007)