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  1. No Access

    Article

    Diagnostic and Dosimetry Features of [64Cu]CuCl2 in High-Grade Paediatric Infiltrative Gliomas

    Paediatric diffuse high-grade gliomas (PDHGG) are rare central nervous system neoplasms lacking effective therapeutic options. Molecular imaging of tumour metabolism might identify novel diagnostic/therapeutic...

    Francesco Fiz, Gianluca Bottoni, Martina Ugolini in Molecular Imaging and Biology (2023)

  2. No Access

    Article

    Head-to-head comparison among 18F-choline PET/CT, 4D contrast-enhanced CT, and 18F-choline PET/4D contrast-enhanced CT in the detection of hyperfunctioning parathyroid glands: a systematic review and meta-analysis

    In primary hyperparathyroidism (PHPT), the localization of hyperfunctioning parathyroid gland (HPTG) allows tailored surgery. Although Four-Dimensional Contrast-enhanced Computed Tomography (4DCeCT) and 18F-choli...

    Arnoldo Piccardo, Gianluca Bottoni, Luis Alejandro Boccalatte in Endocrine (2021)

  3. No Access

    Article

    The role of the deep convolutional neural network as an aid to interpreting brain [18F]DOPA PET/CT in the diagnosis of Parkinson’s disease

    To test the performance of a 3D convolutional neural network (CNN) in analysing brain [18F]DOPA PET/CT in order to identify patients with nigro-striatal neurodegeneration. We evaluated the robustness of the 3D CN...

    Arnoldo Piccardo, Roberto Cappuccio, Gianluca Bottoni, Diego Cecchin in European Radiology (2021)

  4. No Access

    Article

    How to better stratify the risk of differentiated thyroid carcinomas: the key role of radioactive iodine therapy, age, and gender

    The risk of relapse of differentiated thyroid carcinomas (DTC) and their indication for radioactive iodine therapy (RAI) are assessed according to ATA risk stratification system principally based on tumor-node...

    Arnoldo Piccardo, Giacomo Siri in European Journal of Nuclear Medicine and M… (2021)

  5. No Access

    Article

    Head-to-head comparison between 18F-FDG PET/low-dose CT and 18F-FDG PET/contrast-enhanced CT in relapsing ovarian carcinoma: a systematic review and meta-analysis

    Imaging with 18F-FDG PET/CT represents the cornerstone in identifying ovarian cancer (OC) relapse, granting a significantly higher diagnostic accuracy than conventional imaging with CT or MR. Usually, 18F-FDG PET...

    Michela Massollo, Giorgio Treglia, Pierpaolo Trimboli in Clinical and Translational Imaging (2021)

  6. No Access

    Article

    Diagnostic value of retrospectively fused 64CuCl2 PET/MRI in biochemical relapse of prostate cancer: comparison with fused 18F-Choline PET/MRI, 64CuCl2 PET/CT, 18F-Choline PET/CT, and mpMRI

    To assess the diagnostic value of retrospectively fused PET/MRI by comparing the detection rates (DRs) of fused 64CuCl2 PET/MRI vs. fused 18F-Choline PET/MRI in patients with suspected prostatic cancer (PCa) recu...

    Francesco Paparo, Alice Peirano, João Matos, Lorenzo Bacigalupo in Abdominal Radiology (2020)

  7. No Access

    Article

    Indeterminate thyroid nodules. The role of 18F-FDG PET/CT in the “era” of ultrasonography risk stratification systems and new thyroid cytology classifications

    To evaluate the reliability of 18F-FDG PET/CT in distinguishing differentiated thyroid cancers (DTCs) and follicular neoplasms (FNs) from nodular hyperplasias (NH) in thyroid nodules with indeterminate cytology a...

    Arnoldo Piccardo, Matteo Puntoni, Marih Dezzana, Gianluca Bottoni in Endocrine (2020)

  8. Article

    Open Access

    Biokinetic and dosimetric aspects of 64CuCl2 in human prostate cancer: possible theranostic implications

    The aim of the present study is to evaluate the kinetics and dosimetry of 64CuCl2 in human prostate cancer (PCa) lesions.

    Sergio Righi, Martina Ugolini, Gianluca Bottoni, Matteo Puntoni in EJNMMI Research (2018)