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  1. Article

    Open Access

    Epitope-specific immunity against Staphylococcus aureus coproporphyrinogen III oxidase

    Staphylococcus aureus represents a serious infectious threat to global public health and a vaccine against S. aureus represents an unmet medical need. We here characterise two S. aureus vaccine candidates, coprop...

    Alexander Klimka, Sonja Mertins, Anne Kristin Nicolai, Liza Marie Rummler… in npj Vaccines (2021)

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  2. Article

    Open Access

    NOX enzymes as drug targets

    Karl-Heinz Krause, David Lambeth, Martin Krönke in Cellular and Molecular Life Sciences (2012)

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  3. No Access

    Article

    Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

    Granules containing perforin and granzymes are secreted from cytotoxic T lymphocytes. Krönke and co-workers find that acid sphingomyelase is needed for granule shrinkage just before exocytosis in this process.

    Jasmin Herz, Julian Pardo, Hamid Kashkar, Michael Schramm… in Nature Immunology (2009)

  4. No Access

    Article

    Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes

    Soluble HLA class I molecules (sHLAs) have been identified in the serum of patients with inflammatory diseases, allografts and autoimmune diseases and in serum of healthy individuals. The biological significan...

    Nicholaus Zavazava, Martin Krönke in Nature Medicine (1996)