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Open AccessMetabolic route computation in organism communities
Microbiomes are complex aggregates of organisms, each of which has its own extensive metabolic network. A variety of metabolites are exchanged between the microbes. The challenge we address is understanding th...
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Article
Open AccessComputing minimal nutrient sets from metabolic networks via linear constraint solving
As more complete genome sequences become available, bioinformatics challenges arise in how to exploit genome sequences to make phenotypic predictions. One type of phenotypic prediction is to determine sets of ...
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Article
Beyond the genome (BTG) is a (PGDB) pathway genome database: HumanCyc
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Open AccessComputational prediction of human metabolic pathways from the complete human genome
We present a computational pathway analysis of the human genome that assigns enzymes encoded therein to predicted metabolic pathways. Pathway assignments place genes in their larger biological context, and are...