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Outbreak.info Research Library: a standardized, searchable platform to discover and explore COVID-19 resources
Outbreak.info Research Library is a standardized, searchable interface of coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) publications, clinical trials, dat...
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Outbreak.info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations
In response to the emergence of SARS-CoV-2 variants of concern, the global scientific community, through unprecedented effort, has sequenced and shared over 11 million genomes through GISAID, as of May 2022. T...
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Open AccessPredicting the evolution of the Lassa virus endemic area and population at risk over the next decades
Lassa fever is a severe viral hemorrhagic fever caused by a zoonotic virus that repeatedly spills over to humans from its rodent reservoirs. It is currently not known how climate and land use changes could aff...
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Open AccessWastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at scale, especially ...
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Open AccessRegional connectivity drove bidirectional transmission of SARS-CoV-2 in the Middle East during travel restrictions
Regional connectivity and land travel have been identified as important drivers of SARS-CoV-2 transmission. However, the generalizability of this finding is understudied outside of well-sampled, highly connect...
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Evidence of zoonotic transmission of VP6 and NSP4 genes into human species A rotaviruses isolated in Pakistan in 2010
Introduction of animal group A rotavirus (RVA) gene segments into the human RVA population is a major factor sha** the genetic landscape of human RVA strains. The VP6 and NSP4 genes of 74 G/P-genotyped RVA i...
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Open AccessHighly diverse population of Picornaviridae and other members of the Picornavirales, in Cameroonian fruit bats
The order Picornavirales represents a diverse group of positive-stranded RNA viruses with small non-enveloped icosahedral virions. Recently, bats have been identified as an important reservoir of several highly p...
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Open AccessErratum: Emergence of human G2P[4] rotaviruses containing animal derived gene segments in the post-vaccine era
Scientific Reports 6: Article number: 36841; published online: 14 November 2016; updated: 03 January 2017 The original version of this Article contained an error in the name of the first author Mark Zeller whi...
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Open AccessEmergence of human G2P[4] rotaviruses containing animal derived gene segments in the post-vaccine era
The introduction of Rotarix into the Belgian immunization program in June 2006 coincided with an increase of the relative prevalence of G2P[4] strains. However, the genetic composition of these persistent G2P[...
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Reassortment among picobirnaviruses found in wolves
We conducted a viral metagenomics study in diarrheic free-ranging wolves in Portugal, revealing for the first time the presence of reassortant picobirnaviruses. These viruses shared identical capsid segments t...
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Open AccessNovel highly divergent reassortant bat rotaviruses in Cameroon, without evidence of zoonosis
Bats are an important reservoir for zoonotic viruses. To date, only three RVA strains have been reported in bats in Kenya and China. In the current study we investigated the genetic diversity of RVAs in fecal ...
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Open AccessExperimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures
Feline infectious peritonitis (FIP) results from mutations in the viral genome during a common feline enteric coronavirus (FECV) infection. Since many virological and immunological data on FECV infections are ...
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Open AccessDid Large-Scale Vaccination Drive Changes in the Circulating Rotavirus Population in Belgium?
Vaccination can place selective pressures on viral populations, leading to changes in the distribution of strains as viruses evolve to escape immunity from the vaccine. Vaccine-driven strain replacement is a m...
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Open AccessModular approach to customise sample preparation procedures for viral metagenomics: a reproducible protocol for virome analysis
A major limitation for better understanding the role of the human gut virome in health and disease is the lack of validated methods that allow high throughput virome analysis. To overcome this, we evaluated th...
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Open AccessComparative analysis of pentavalent rotavirus vaccine strains and G8 rotaviruses identified during vaccine trial in Africa
RotaTeqTM is a pentavalent rotavirus vaccine based on a bovine rotavirus genetic backbone in vitro reassorted with human outer capsid genes. During clinical trials of RotaTeqTM in Sub-Saharan Africa, the vaccine ...
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Open AccessFecal virome analysis of three carnivores reveals a novel nodavirus and multiple gemycircularviruses
More knowledge about viral populations in wild animals is needed in order to better understand and assess the risk of zoonotic diseases. In this study we performed viral metagenomic analysis of fecal samples f...
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Genotypes of rotavirus strains circulating in Amman, Jordan, in 2006/07 and their significance for the potential effectiveness of future rotavirus vaccination
The prevalence, seasonality and genotypes of rotavirus circulating in Jordan were determined to provide data useful for the implementation of a rotavirus vaccine in the national childhood vaccination program. ...
