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Protocol
Isolation of Mouse Germ Cells by FACS Using Hoechst 33342 and SYTO16 Double Staining
In the adult mouse testis, germ cells of various developmental cell states co-exist. FACS isolation of cells stained with the DNA dye Hoechst 33342 has been used for many years to sub-divide these cells based ...
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Article
Looking with new eyes: advanced microscopy and artificial intelligence in reproductive medicine
Microscopy has long played a pivotal role in the field of assisted reproductive technology (ART). The advent of artificial intelligence (AI) has opened the door for new approaches to sperm and oocyte assessmen...
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Article
Open AccessAltered DNA methylation in estrogen-responsive repetitive sequences of spermatozoa of infertile men with shortened anogenital distance
It has been suggested that antenatal exposure to environmental endocrine disruptors is responsible for adverse trends in male reproductive health, including male infertility, impaired semen quality, cryptorchi...
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Article
Transcriptome and translatome co-evolution in mammals
Gene-expression programs define shared and species-specific phenotypes, but their evolution remains largely uncharacterized beyond the transcriptome layer1. Here we report an analysis of the co-evolution of trans...
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Article
Reconstructing sex chromosome evolution
