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Article
Open AccessSymptomatic post COVID patients have impaired alveolar capillary membrane function and high VE/VCO2
Post COVID-19 syndrome is characterized by several cardiorespiratory symptoms but the origin of patients’ reported symptomatology is still unclear.
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Article
Open AccessLooking into the Kinetics of NT-proBNP and sST2 Changes in Patients with Heart Failure Treated with Sacubitril/Valsartan: A Hint to Different Therapeutic Pathways
N-terminal pro-B-type natriuretic peptide (NT-proBNP) and soluble interleukin 1 receptor-like 1 ST2 (sST2) are biomarkers used to grade heart failure with reduced ejection fraction (HFrEF) severity. Both are p...
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Article
Open AccessDigital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients
Patients requiring diagnostic testing for coronavirus disease 2019 (COVID-19) are routinely assessed by reverse-transcription quantitative polymerase chain reaction (RT-qPCR) amplification of Sars-CoV-2 virus ...
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Article
Open AccessPrognostic impact of admission high-sensitivity C-reactive protein in acute myocardial infarction patients with and without diabetes mellitus
High-sensitivity C-reactive protein (hs-CRP) elevation frequently occurs in acute myocardial infarction (AMI) and is associated with adverse outcomes. Since diabetes mellitus (DM) is characterized by an underl...
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Article
Darunavir-based dual therapy of treatment-experienced HIV-infected patients: analysis from a national multicenter database
We assessed the virological response of dual therapy with DRV/r, plus raltegravir, maraviroc or etravirine, in virological failure patients and in virologically suppressed patients collected in the Italian Ant...
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Article
Type I collagen and matrix metalloproteinase 1, 3 and 9 gene polymorphisms in the predisposition to pelvic organ prolapse
To evaluate whether the presence of specific polymorphism in the gene promoter of collagen and some matrix metalloproteinases was associated with the risk of develo** pelvic organ prolapse.
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Article
Serum N-terminal pro-brain natriuretic peptide, a marker of skin thickness in systemic sclerosis?
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Article
Genetic Contribution to Carotid Vascular Disease in Patients with Systemic Lupus Erythematosus
We investigated whether stromelysin, a candidate gene in atherogenesis, plays a role in atherogenesis of systemic lupus erythematosus (SLE), a leading cause of mortality in SLE.
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Article
PPAR-γ2 Pro12Ala Variant, Insulin Resistance and Plasma Long-chain Polyunsaturated Fatty Acids in Childhood Obesity
Pro12Ala variant of peroxisome-proliferator-activated receptor-gamma2 (PPAR-γ2) may be linked to insulin sensitivity. This study examined whether an association of PPAR-γ2 Pro12Ala with insulin resistance and ...
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Article
l-Arginine therapy in Raynaud's phenomenon?
Sincel-Arginine is the substrate for nitric oxide synthesis by vascular endothelial cells the effects ofl-arginine treatment on the digital vascular response to local stimuli were investigated in patients with pr...
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Article
Liquid chromatographic determination of free serotonin in human plasma
The complex background of interfering substances makes plasma pretreatment necessary before performing liquid-chromatographic quantitation of circulating serotonin. We compared two isolation procedures (extrac...
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Article
Quantitative determination of serotonin released from human platelets
A high-performance liquid chromatographic technique has been used for measuring the amount of endogenous serotonin (5-hydroxytryptamine, 5-HT) released from human platelets stimulated by adenosine diphosphate ...
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Article
High-performance liquid chromatographic assay of serotonin in human plasma
A sensitive and reproducible reversed-phase high-performance liquid chromatography with electrochemical detection for determination of serotonin in human plasma is described. The method has an average coeffici...
