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Open AccessDevelopmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex
Endocannabinoids provide control over cortical neurotransmission. We investigated the developmental expression of key genes in the endocannabinoid system across human postnatal life and determined whether they...
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Article
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
Andy Feinberg and colleagues show in a colon cancer model that most DNA methylation alterations occur in sequence regions distinct from promoters or canonical CpG islands, termed 'CpG island shores', and that ...
