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  1. No Access

    Article

    Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

    Christopher Newton-Cheh and colleagues report genome-wide association analyses for QT interval, an electrocardiographic measure reflecting myocardial repolarization, in 100,000 individuals. They identify 35 lo...

    Dan E Arking, Sara L Pulit, Lia Crotti, Pim van der Harst… in Nature Genetics (2014)

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    Chapter

    Role of Striatal A2A Receptor Subpopulations in Neurological Disorders

    A very significant density of adenosine A2A receptors (A2AR) is present in the striatum, where they are preferentially localized postsynaptically in enkephalinergic-GABAergic-medium spiny neurons (enkephalinergic...

    Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart, Seema Gulyani… in Adenosine (2013)

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    Article

    Common variants at ten loci modulate the QT interval duration in the QTSCD Study

    Arne Pfeufer, Aravinda Chakravarti and colleagues from the QTSCD consortium report genetic associations influencing the QT interval duration, a measure of cardiac repolarization which is a risk factor for sudd...

    Arne Pfeufer, Serena Sanna, Dan E Arking, Martina Müller, Vesela Gateva… in Nature Genetics (2009)