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Chapter
Toxic and Metabolic Disorders
Metabolic diseases are mostly congenital inborn errors leading to functional defects in metabolic pathways, whereas toxic and metabolic diseases in adults are usually acquired. MRI is the cornerstone in the as...
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Article
Open AccessBrain BOLD MRI O2 and CO2 stress testing: implications for perioperative neurocognitive disorder following surgery
Mechanical ventilation to alter and improve respiratory gases is a fundamental feature of critical care and intraoperative anesthesia management. The range of inspired O2 and expired CO2 during patient management...
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Chapter
Toxic and Metabolic Disorders: Metabolic Diseases
In metabolic diseases we normally differentiate between congenital and acquired diseases.
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Chapter
CT Diagnostics in Brain Tumors
Brain tumors are among the top causes of cancer-related deaths both in Europe and North America.
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Article
Good clinical and MRI outcome after arthroscopic autologous chondrocyte implantation for cartilage repair in the knee
To analyze the clinical outcome and cartilage regeneration after all-arthroscopic Autologous Chondrocyte Implantation (ACI) using chondrospheres® (ACT3D) for the treatment of full-size articular cartilage lesi...
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Article
Prospective intraindividual comparison of gadoterate and gadobutrol for cervical and intracranial contrast-enhanced magnetic resonance angiography
Gadobutrol (GB) is reported to provide improved relaxivity and concentration compared to gadoterate (GT). This study was designed to intraindividually compare quantitative and qualitative enhancement character...
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Article
Open AccessDisk displacement, eccentric condylar position, osteoarthrosis – misnomers for variations of normality? Results and interpretations from an MRI study in two age cohorts
Clinical decision-making and prognostic statements in individuals with manifest or suspected temporomandibular disorders (TMDs) may involve assessment of (a) the position of articular disc relative to the mand...
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Chapter
Movement Disorders and Metabolic Disease
Movement disorders include a large number of diseases that clinically present as neurological conditions that affect the speed, quality, fluency or ease of movements. Clinically movement disorders can present ...
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Article
High-resolution blood-pool-contrast-enhanced MR angiography in glioblastoma: tumor-associated neovascularization as a biomarker for patient survival. A preliminary study
The objective of the study was to determine whether tumor-associated neovascularization on high-resolution gadofosveset-enhanced magnetic resonance angiography (MRA) is a useful biomarker for predicting surviv...
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Article
Characterization and therapy monitoring of head and neck carcinomas using diffusion-imaging-based intravoxel incoherent motion parameters—preliminary results
Using the intravoxel incoherent motion (IVIM) model, diffusion-related coefficient (D) and perfusion-related parameter (f) can be measured. Here, we used IVIM imaging to characterize squamous cell carcinomas of h...
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Article
Albumin-binding MR blood pool contrast agent improves diagnostic performance in human brain tumour: comparison of two contrast agents for glioblastoma
We qualitatively and quantitatively compared MRI enhancement obtained with gadofosveset, an albumin-binding blood-pool contrast agent, and with gadobutrol, an extracellular contrast agent, in patients with gli...
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Chapter and Conference Paper
Perspectives of 3 T Magnetic Resonance Imaging in Radiosurgical Treatment Planning
The introduction of 3 T magnetic resonance imaging (MRI) scanners for neuro-oncological diagnostics showed a general improvement of image quality, especially in terms of the detection and differentiation of in...
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Chapter and Conference Paper
Degenerative Brain Disease and Aging
With the increase of the mean age of the populations, neurodegenerative diseases are becoming more and more important. Early diagnosis is of particular importance to allow for early therapeutic intervention, a...
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Article
Changes in AVM angio-architecture and hemodynamics after stereotactic radiosurgery assessed by dynamic MRA and phase contrast flow assessments
Assessment of changes in the hemodynamics of Arteriovenous malformations (AVM) induced by radiosurgery by MR Phase contrast (PC) measurements of the internal carotid arteries (ICA).
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Article
Automated MR morphometry to predict Alzheimer’s disease in mild cognitive impairment
Prediction of progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) is challenging but essential for early treatment. This study aims to investigate the use of hippocampal atrophy marker...
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Article
High-relaxivity contrast-enhanced magnetic resonance neuroimaging: a review
Evaluation of brain lesions using magnetic resonance imaging (MRI) provides information that is critical for accurate diagnosis, prognosis, therapeutic intervention and monitoring response. Conventional contra...
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Article
Detection of IDH1 mutations in gliomatosis cerebri, but only in tumors with additional solid component: evidence for molecular subtypes
The current WHO classification of brain tumors defines gliomatosis cerebri (GC) as an extensively infiltrating astrocytic glioma involving at least three cerebral lobes. The relation of GC to diffuse astrocyto...
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Article
Human brain tumor imaging with a protein-binding MR contrast agent: initial experience
Gadofosveset is a Gd-based protein-binding blood pool agent with increased relaxivities and blood half-life compared with conventional Gd-based contrast agents (GBCAs). No experience exists about the use of ga...
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Chapter and Conference Paper
Vorhersage des Krankheitsverlaufes von leichten kognitiven Beeinträchtigungen durch automatisierte MRT Morphometrie
Die leichte kognitive Beeinträchtigung (LKB) gilt als Anzeichen für ein erhöhtes Risiko der Entwicklung einer Alzheimerdemenz. Eine fundierte klinische Prognose für den Krankheitsverlauf kann aber bis dato nic...
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Article
Head and Neck Imaging
Neuroimaging techniques play a central role in the diagnosis and management of Central nervous system (CNS) diseases. The use of Magnetic Resonance Imaging (MRI) has helped to diagnose and understand disease p...
