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  1. Article

    Open Access

    Modern Management of Cardiometabolic Continuum: From Overweight/Obesity to Prediabetes/Type 2 Diabetes Mellitus. Recommendations from the Eastern and Southern Europe Diabetes and Obesity Expert Group

    The increasing global incidence of obesity and type 2 diabetes mellitus (T2D) underscores the urgency of addressing these interconnected health challenges. Obesity enhances genetic and environmental influences...

    Andrej Janez, Emir Muzurovic, Pawel Bogdanski, Leszek Czupryniak in Diabetes Therapy (2024)

  2. Article

    Open Access

    The Effect of Sodium–Glucose Cotransporter Inhibitors on Renal Function as Adjunctive to Insulin in Adults with Type 1 Diabetes: An Updated Multilevel Meta-analysis of Randomized Controlled Trials

    This systematic review aimed to summarize the existing evidence from published randomized controlled trials (RCTs) on the impact of sodium–glucose cotransporter (SGLT) inhibitors on albuminuria levels and rena...

    Paschalis Karakasis, Djordje S. Popovic, Dimitrios Patoulias in Diabetes Therapy (2024)

  3. Article

    Open Access

    Correction to: New-Onset Diabetes Mellitus in COVID-19: A Sco** Review

    Anca Pantea Stoian, Ioana-Cristina Bica, Teodor Salmen, Wael Al Mahmeed in Diabetes Therapy (2024)

  4. Article

    Open Access

    New-Onset Diabetes Mellitus in COVID-19: A Sco** Review

    The coronavirus disease 2019 (COVID-19) pandemic became superimposed on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection alters the metabolic equilibrium, it may induce p...

    Anca Pantea Stoian, Ioana-Cristina Bica, Teodor Salmen, Wael Al Mahmeed in Diabetes Therapy (2024)

  5. Article

    Open Access

    Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19

    SARS-CoV-2 pandemic has caused a collapse of the world health systems. Now, vaccines and more effective therapies have reversed this crisis but the scenario is further aggravated by the appearance of a new pat...

    Pasquale Picone, Tiziana Sanfilippo in Cellular and Molecular Neurobiology (2023)

  6. Article

    Open Access

    Semaglutide in Obesity: Unmet Needs in Men

    Mojca Jensterle, Manfredi Rizzo, Andrej Janež in Diabetes Therapy (2023)

  7. Article

    Open Access

    Absolute Hyperglycemia versus Stress Hyperglycemia Ratio for the Prognosis of Hospitalized Patients with COVID-19 in the First Months of the Pandemic: A Retrospective Study

    Diabetes is a risk factor for greater severity of coronavirus disease 2019 (COVID-19). The stress hyperglycemia ratio (SHR) is an independent predictor of critical illness, and it is reported to have a stronge...

    Alexandra A. Matias, Inês Manique, Teresa Sabino, Teresa Rego in Diabetes Therapy (2023)

  8. No Access

    Chapter

    Clinical Efficacy of Proprotein Convertase Synthase Kexin Type 9 Inhibition in Persons with Diabetes Mellitus

    Diabetes mellitus (DM) is associated with atherogenic dyslipidemia and heightened systemic inflammatory, oxidative, and thrombotic tones. These metabolic abnormalities greatly increase the risk for atheroscler...

    Peter P. Toth, Manfredi Rizzo, Maciej Banach in Lipoproteins in Diabetes Mellitus (2023)

  9. Article

    Open Access

    Use of glucagon in severe hypoglycemia is scarce in most countries, and has not been expanded by new ready-to-use glucagons

    Glucagon (traditional kits for intramuscular administration, Glucagon and Glucagen), although recommended as a remedy for severe hypoglycemia (SH), has been reported to be under-utilized, likely because of tec...

    Antonio E. Pontiroli, Manfredi Rizzo, Elena Tagliabue in Diabetology & Metabolic Syndrome (2022)

  10. Article

    Open Access

    Personalized management of dyslipidemias in patients with diabetes—it is time for a new approach (2022)

    Dyslipidemia in patients with type 2 diabetes (DMT2) is one of the worst controlled worldwide, with only about 1/4 of patients being on the low-density lipoprotein cholesterol (LDL-C) target. There are many re...

    Maciej Banach, Stanisław Surma, Zeljko Reiner, Niki Katsiki in Cardiovascular Diabetology (2022)

  11. Article

    Open Access

    The Dual Pandemics of COVID-19 and Obesity: Bidirectional Impact

    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, has been shown to disrupt many organ systems in the human body. Though several medical disorders have be...

    Nitin Kapoor, Sanjay Kalra, Wael Al Mahmeed, Khalid Al-Rasadi in Diabetes Therapy (2022)

  12. No Access

    Article

    The effect of statin therapy in combination with ezetimibe on circulating C-reactive protein levels: a systematic review and meta-analysis of randomized controlled trials

    Previous studies have reported that statin or ezetimibe therapy has an anti-inflammatory effect. However, the results of individual studies on the effect of statin therapy in combination with ezetimibe on C-re...

    Seyyed Mostafa Arabi, Mahla Chambari, Mahsa Malek-Ahmadi in Inflammopharmacology (2022)

  13. Article

    Efficacy of GLP-1 RA Approved for Weight Management in Patients With or Without Diabetes: A Narrative Review

    The approval of once daily liraglutide, 3.0 mg, and once weekly semaglutide, 2.4 mg, for chronic weight management provides a novel effective strategy against obesity. The reliable models that might predict we...

    Mojca Jensterle, Manfredi Rizzo, Martin Haluzík, Andrej Janež in Advances in Therapy (2022)

  14. Article

    Open Access

    Effect of Oral Semaglutide on Cardiovascular Parameters and Their Mechanisms in Patients with Type 2 Diabetes: Rationale and Design of the Semaglutide Anti-Atherosclerotic Mechanisms of Action Study (SAMAS)

    Type 2 diabetes (T2D) management has reached a point where not only optimal glycaemic control is necessary, but also additional interventions with proven cardiovascular risk reduction benefit. Subcutaneous sem...

    Miodrag Janić, Manfredi Rizzo, Francesco Cosentino, Anca Pantea Stoian in Diabetes Therapy (2022)

  15. Article

    Open Access

    Liraglutide Improved Cardiometabolic Parameters More in Obese than in Non-obese Patients with Type 2 Diabetes: A Real-World 18-Month Prospective Study

    The glucagon-like peptide-1 agonist (GLP1-RA) liraglutide is currently approved for the treatment of both obesity and type 2 diabetes (T2DM). We investigated whether the effect of this agent on cardiometabolic...

    Dragana Nikolic, Angelo M. Patti, Rosaria V. Giglio, Roberta Chianetta in Diabetes Therapy (2022)

  16. No Access

    Article

    Glucose transporter 4 mRNA expression in subcutaneous adipose tissue of women with PCOS remains unchanged despite metformin withdrawal: is there a cellular metabolic treatment legacy effect?

    Metformin induces GLUT-4 mRNA expression in insulin target tissues in PCOS. It is unclear how long this impact is sustained after withdrawal of metformin. We aimed to compare the effect of metformin withdrawal...

    Mojca Jensterle, Nika Aleksandra Kravos, Vita Dolžan, Katja Goričar in Endocrine (2022)

  17. Article

    Glycemic Variability, Glycated Hemoglobin, and Cardiovascular Complications: Still a Dilemma in Clinical Practice

    Antonio Ceriello, Ali A. Rizvi, Manfredi Rizzo in Advances in Therapy (2022)

  18. Article

    Open Access

    Use of Novel Antidiabetic Agents in Patients with Type 2 Diabetes and COVID-19: A Critical Review

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The latter is a pandemic that has the potential of develo** into a severe illness manifesting as syste...

    Djordje S. Popovic, Nikolaos Papanas, Anca Pantea Stoian, Ali A. Rizvi in Diabetes Therapy (2021)

  19. Article

    Open Access

    Nutraceuticals in the Management of Dyslipidemia: Which, When, and for Whom? Could Nutraceuticals Help Low-Risk Individuals with Non-optimal Lipid Levels?

    The aim of this review is to summarize the available clinical efficacy and safety data related to the most studied and used lipid-lowering nutraceuticals.

    Arrigo F. G. Cicero, Federica Fogacci in Current Atherosclerosis Reports (2021)

  20. Article

    Open Access

    New Sub-Phenoty** of Subjects at High Risk of Type 2 Diabetes: What Are the Potential Clinical Implications?

    Prediabetes is defined as a condition of abnormal glucose metabolism, characterised by plasma glucose above normal range but not as high as required for the diagnosis of diabetes mellitus (DM). It represents a...

    Djordje S. Popovic, Manfredi Rizzo, Edita Stokic, Nikolaos Papanas in Diabetes Therapy (2021)

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