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  1. Article

    Open Access

    Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion

    Our understanding of the key phosphorylation-dependent signalling pathways in the human malaria parasite, Plasmodium falciparum, remains rudimentary. Here we address this issue for the essential cGMP-dependent pr...

    Mahmood M. Alam, Lev Solyakov, Andrew R. Bottrill in Nature Communications (2015)

  2. Article

    Open Access

    Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

    The role of protein phosphorylation in the life cycle of malaria parasites is slowly emerging. Here we combine global phospho-proteomic analysis with kinome-wide reverse genetics to assess the importance of pr...

    Lev Solyakov, Jean Halbert, Mahmood M. Alam, Jean-Philippe Semblat in Nature Communications (2011)