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  1. No Access

    Article

    Effects of Oxytocin Pathway Gene Polymorphisms and Adverse Childhood Experiences on the Recognition of Emotion in Schizophrenia Spectrum Disorders

    Objectives. To assess the role of interactions between oxytocin pathway gene polymorphisms and adverse childhood experiences (ACE) in deficits of the recognition of emotion in schizophrenia. Materials and methods

    M. V. Alfimova, V. A. Mikhailova, M. V. Gabaeva… in Neuroscience and Behavioral Physiology (2024)

  2. No Access

    Article

    Genetic Polymorphism of Cytokines IL-1β, IL-4, and TNF-α as a Factor Modifying the Influence of Adverse Childhood Experiences on the Symptoms of Schizophrenia

    Objectives. Working from the hypothesis that activation of the immune system is one of the mechanisms whereby early environmental factors influence the onset and course of schizophrenia, we studied the effects o...

    M. V. Alfimova, G. I. Korovaitseva, M. V. Gabaeva… in Neuroscience and Behavioral Physiology (2023)

  3. No Access

    Article

    Prognostication of Functional Outcomes of Schizophrenia Using a Multigene Panel

    Objectives. To compare groups of schizophrenia patients with different levels of functional outcomes and different frequencies of risk variants at polymorphic loci of five candidate genes to create a multigene p...

    S. A. Golubev, T. V. Lezheiko, G. I. Korovaitseva… in Neuroscience and Behavioral Physiology (2022)

  4. No Access

    Article

    Studies of the Association of Genetic Polymorphism C677T in the Methylenetetrahydrofolate Reductase Gene with Symptom Severity in Schizophrenia Patients

    Objective. To study the association of the C677T polymorphism of the MTHFR gene with the risk of develo** schizophrenia in a large cohort including patients with schizophrenia and mentally healthy people and to...

    G. I. Korovaitseva, M. V. Gabaeva, V. E. Golimbet in Neuroscience and Behavioral Physiology (2021)

  5. No Access

    Article

    Association of Genes for Proinflammatory Cytokines and Depression

    Objectives. To study the association between proinflammatory cytokines and depression. Materials and methods. The: IL-1β C-511T and TNF-α G-308A gene polymorphisms were studied in patients with diagnoses of “depr...

    T. V. Lezheiko, A. V. Andryushchenko… in Neuroscience and Behavioral Physiology (2019)

  6. No Access

    Article

    Studies of the Effects of Genes for Inflammatory Factors on Basic Personality Dimensions

    Objective. To study the relationship between the basic personality dimensions and genes encoding various inflammation mediators and biomarkers whose contents are elevated in schizophrenia...

    V. E. Golimbet, M. V. Alfimova… in Neuroscience and Behavioral Physiology (2017)

  7. No Access

    Article

    The Val66Met BDNF Polymorphism Has No Effect on Cognitive Deficit in Schizophrenia Patients or the Risk of This Disease in Their Relatives

    Objective. The brain-derived neurotrophic factor gene (BDNF) is a presumptive candidate gene for schizophrenia. Results from many studies have pointed to the absence of any association be...

    M. V. Alfimova, V. E. Golimbet… in Neuroscience and Behavioral Physiology (2016)