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Article
Open AccessThree-dimensional gravity modelling of a Quaternary overdeepening fill in the Bern area of Switzerland discloses two stages of glacial carving
The geometry of glacial overdeepenings on the Swiss Plateau close to Bern was inferred through a combination of gravity data with a 3D gravity modelling software. The target overdeepenings have depths between ...
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Article
Technology-based measurements for screening, monitoring and preventing frailty
Sensor technology, in particular wearable inertial sensors, has the potential to help researchers objectively assess the functionality of older adults. The following review provides an overview about the possi...
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Article
Model development to study strategies of younger and older adults getting up from the floor
Long lies after a fall remain a public health challenge. Many successful fall prevention programmes have been developed but only few of them include recovery strategies after a fall. Once better understood, su...
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Article
Development of a standard fall data format for signals from body-worn sensors
Objective measurement of real-world fall events by using body-worn sensor devices can improve the understanding of falls in older people and enable new technology to prevent, predict, and automatically recogni...
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Article
Patienten mit Begleitdiagnose Demenz
Mehr als ein Drittel der Patienten in der stationären geriatrischen Rehabilitation weist eine demenzielle Erkrankung als Nebendiagnose auf. Aufgrund der demographischen Entwicklung ist zukünftig mit einer stei...
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Article
Empfehlungen für die Durchführung des motorischen Assessments der unteren Extremität zur ICF-basierten Verlaufsbeurteilung der Mobilität in der stationären geriatrischen Rehabilitation
Aufgrund steigender Nachfrage nach geriatrischen Rehabilitationsleistungen zwingen begrenzte Ressourcen zu objektiven und transparenten Allokationsentscheidungen. Ziel einer interdisziplinären Konsensusgruppe ...
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Article
Stimulation of acupoint ST-34 acutely improves gait performance in geriatric patients during rehabilitation: A randomized controlled trial
To determine whether a specific regimen of acupoint stimulation improved gait performance in geriatric patients.
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Article
Dokumentation in der gynäkologischen Onkologie
Der in den letzten Jahrzenten rasant zunehmende Dokumentationsaufwand in der Medizin hat sich auch auf die gynäkologische Onkologie ausgewirkt. Speziell die Notwendigkeit, maligne Erkrankungen sowohl longitudi...
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Article
Aufgaben der regulatorischen Toxikologie
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Article
Children as a sensitive subgroup and their role in regulatory toxicology: DGPT workshop report
There is increasing discussion that children might be considered as a specific subgroup in public health regulations which could be more sensitive than the average "adult" human being. Differences between chi...
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Article
Isolation, identification and quantitative evaluation of specific cell types from the mammalian gastric mucosa
Functional in vitro studies with isolated gastric mucosal cells require cytological identification of different cell types in suspension or primary culture. Since suitable techniques have not been well establi...
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Article
Magnesium-L-aspartate-HCl and magnesium-oxide: bioavailability in healthy volunteers
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Chapter and Conference Paper
Transport of Taurocholate in Isolated Cells from Ileum, Liver and Kidney
Bile acid carriers are localized in ileum, liver, and kidney. It is unknown whether these carriers are identical or different. This work uses isolated cells of the three organs to compare the uptake kinetics o...
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Chapter and Conference Paper
Isolated Intestinal Cells of Guinea Pig: A Suitable Model for Assessing Direct Toxic Effects of Ethanol on the Mucosa of the Upper Small Intestine
The effects of acute ethanol (1–10%) on membrane transport and respiration in isolated jejunal cells of guinea pig were investigated.
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Article
Lack of intestinal transport of [3H]-demethylphalloin: Comparative studies with phallotoxins and bile acids on isolated small intestinal cells and ileal brush border membrane vesicles
Several earlier studies suggested that the uptake of phallotoxins by liver cells is a carrier mediated process using a transport system normally handling bile acids (see Frimmer 1982). In this study we have sh...
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Chapter and Conference Paper
An Experimental Model for the Study of Hepatic Transport and Metabolism of Toxic Compounds
The usefulness of isolated liver cells for the study of hepatocellular transport and metabolism is demonstrated, using 1-naphthol and 2,2′-dichlorobiphenyl as model compounds. More than 60% of both substances ...
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Article
Bile acid conjugation in the chimpanzee: effective sulfation of lithocholic acid
To characterize the hepatic biotransformation in the chimpanzee of the primary bile acid chenodeoxycholic acid (chenic) and its major bacterial metabolite lithocholic acid (lithocholic) a mixture of tracer amo...
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Chapter and Conference Paper
Chimpanzees Sulfate Lithocholate Similar to Man
Chenodeoxycholic acid is used to dissolve cholesterol gallstones in man. Although extensive biochemical and morphological evidence suggest that the drug is safe in man, widespread usage of this bile acid has b...
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Chapter
The Effect of Conjugation on uptake and Secretion of Lipophilic Compounds by Isolated Hepatocytes
Isolated rat hepatocytes were used to investigate important factors that influence the transhepatic transport of lipophilic compounds (ethinyl estradiol, estrone and naphthol).
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Article
Influence of viability on bromosulfophthalein uptake by isolated hepatocytes
The initial rates of BSP uptake by isolated hepatocytes were compared in cells of good and poor viability. Cells with impaired viability were obtained by ageing or by accident also in fresh preparations. Viabi...
