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Article
Evaluation of drug utilization pattern of antidiabetic drugs and 10-year cardiovascular risk in new and recently diagnosed type 2 diabetes mellitus patients: a prospective, longitudinal, observational, hospital-based study
To evaluate changes in drug utilization pattern of antidiabetic drugs on prospective follow-up of new and recently diagnosed type 2 diabetes mellitus patients along with their 10-year cardiovascular risk asses...
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Article
Open AccessPredicting development of ipilimumab-induced hypophysitis: utility of T4 and TSH index but not TSH
Ipilimumab, a monoclonal antibody inhibiting CLTA-4, is an established treatment in metastatic melanoma, either alone or in combination with nivolumab, and results in immune mediated adverse events, including ...
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Article
Protective effect of black relative to white race against non-alcoholic fatty liver disease in patients with severe obesity, independent of type 2 diabetes
Severe obesity (body mass index ⩾35 kg m−2) and type 2 diabetes (T2D) are potent and additive risk factors for non-alcoholic fatty liver disease (NAFLD), including non-alcoholic steatohepatitis (NASH). Scant avai...
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Article
Synthesis of substituted fatty oxathiolanes and thioethers from an allylic oxo fatty acid ester
Substituted oxathiolane and thioether derivatives have been synthesized from an allylic oxo fatty acid ester. The reaction of methyl 4-oxo-trans-2-octadecenoate with 3-mercaptopropan-1,2-diol (1-thioglycerol) aff...
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Article
Derivatization of keto fatty acids, X: Synthesis of thiazanones
The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds—methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctade...