Abstract
The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds—methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctadecanoate and octadecanal—were allowed to react with β-mercaptopropionic acid in the presence of ammonium carbonate in benzene to give the corresponding 4-m-thiazanones in high yields. The structures of these compounds were confirmed by combustion and spectral data.
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Khan, A., Husain, S.R., Ahmad, F. et al. Derivatization of keto fatty acids, X: Synthesis of thiazanones. Lipids 22, 578–582 (1987). https://doi.org/10.1007/BF02537284
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DOI: https://doi.org/10.1007/BF02537284