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    Article

    Efficacy and safety of myocardial gene transfer of adenovirus, adeno-associated virus and lentivirus vectors in the mouse heart

    Gene therapy is a promising new treatment option for cardiac diseases. For finding the most suitable and safe vector for cardiac gene transfer, we delivered adenovirus (AdV), adeno-associated virus (AAV) and l...

    M Merentie, L Lottonen-Raikaslehto, V Parviainen, J Huusko, S Pikkarainen… in Gene Therapy (2016)

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    Article

    Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis

    The markers of oxidative stress and inflammation were studied in acute pancreatitis in transgenic rats exhibiting activated polyamine catabolism. In addition, the effect of bismethylspermine (Me2Spm) pretreatment...

    M. Merentie, A. Uimari, M. Pietilä, R. Sinervirta, T. A. Keinänen… in Amino Acids (2007)