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    Article

    MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors

    Pancreatic cancer is one of the most lethal malignancies due to its aggressive growth and rapid development of distant metastases. In this context, mucin 1 (MUC1) overexpression and hypoxia are frequently obse...

    S Kitamoto, S Yokoyama, M Higashi, N Yamada, S Takao, S Yonezawa in Oncogene (2013)

  2. Article

    Open Access

    The etiologic role of human papillomavirus in penile cancers: a study in Vietnam

    We investigated the aetiologic role of human papillomavirus (HPV) in 120 penile squamous cell carcinomas (PSCCs) from Vietnam.

    H T T Do, C Koriyama, N A Khan, M Higashi, T Kato, N T Le in British Journal of Cancer (2013)

  3. Article

    Open Access

    Promoter CpG methylation in cancer cells contributes to the regulation of MUC4

    Mucin 4 (MUC4) is a high molecular weight transmembrane mucin that is overexpressed in many carcinomas and is a risk factor associated with a poor prognosis. In this study, we show that the DNA methylation pat...

    N Yamada, Y Nishida, H Tsutsumida, M Goto, M Higashi, M Nomoto in British Journal of Cancer (2009)

  4. Article

    Open Access

    Human papillomavirus detected in female breast carcinomas in Japan

    To investigate the aetiological role of human papillomavirus (HPV) in breast cancer, we examined the presence, genotype, viral load, and physical status of HPV in 124 Japanese female patients with breast carci...

    N A Khan, A Castillo, C Koriyama, Y Kijima, Y Umekita, Y Ohi in British Journal of Cancer (2008)

  5. Article

    Open Access

    Human papillomavirus-16 is integrated in lung carcinomas: a study in Chile

    The human papillomavirus (HPV) was detected in 20 (29%) out of 69 lung carcinomas (LCs) in Chile, by PCR and Southern blot, and was more frequently detected in squamous cell carcinoma (SQC) than in adenocarcin...

    F Aguayo, A Castillo, C Koriyama, M Higashi, T Itoh in British Journal of Cancer (2007)

  6. No Access

    Chapter and Conference Paper

    Clinical usefulness of multidetector CT angiography : application to the diagnosis of arterial occlusive diseases in lower extermities

    Our goal is to establish the utility of multi-detector row CT angiography (MDCTA) for evaluating arterial stenosis in patients with arterial occlusive disease of lower extremities.

    N. Hirai, R. Tanaka, Y. Hori, M. Higashi in CARS 2002 Computer Assisted Radiology and … (2002)