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  1. No Access

    Article

    Incidence rate of severe adverse drug reactions to nonionic contrast media at the National Hospital Organization Osaka National Hospital

    Severe adverse drug reactions in response to intravascular contrast media used in computed tomography, although rare, are potentially life-threatening. This retrospective cohort study aimed to estimate the inc...

    T. Honda, K. Kuriyama, K. Kiso, K. Kishimoto, T. Tsuboyama in Allergo Journal International (2020)

  2. Article

    Open Access

    Efficacy of programmed intermittent bolus epidural analgesia in thoracic surgery: a randomized controlled trial

    Continuous epidural infusion (CEI) has some disadvantages, such as increased local anesthetic consumption and limited area of anesthetic distribution. Programmed intermittent bolus (PIB) is a technique of epid...

    M. Higashi, K. Shigematsu, E. Nakamori, S. Sakurai, K. Yamaura in BMC Anesthesiology (2019)

  3. No Access

    Article

    Metaanalysen zur Messgenauigkeit nichtinvasiver hämodynamischer Überwachungstechnologien bei Erwachsenen

    Nichtinvasive Überwachungstechniken sollen eine exakte, verlässliche, bettseitig verfügbare, kontinuierliche, einfach zu bedienende und kostengünstige Darstellung vitaler Patientenparameter in Anästhesiologie,...

    PD Dr. med. G. Pestel, K. Fukui, M. Higashi, I. Schmidtmann, C. Werner in Der Anaesthesist (2018)

  4. Article

    Open Access

    Effects of cardiopulmonary bypass on the accuracy of non-invasive hemoglobin measurement by pulse co-oximetry

    K Tokuda, K Yamaura, M Higashi, S Hoka in Intensive Care Medicine Experimental (2015)

  5. No Access

    Article

    MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors

    Pancreatic cancer is one of the most lethal malignancies due to its aggressive growth and rapid development of distant metastases. In this context, mucin 1 (MUC1) overexpression and hypoxia are frequently obse...

    S Kitamoto, S Yokoyama, M Higashi, N Yamada, S Takao, S Yonezawa in Oncogene (2013)

  6. Article

    Open Access

    The etiologic role of human papillomavirus in penile cancers: a study in Vietnam

    We investigated the aetiologic role of human papillomavirus (HPV) in 120 penile squamous cell carcinomas (PSCCs) from Vietnam.

    H T T Do, C Koriyama, N A Khan, M Higashi, T Kato, N T Le in British Journal of Cancer (2013)

  7. No Access

    Article

    Unexpectedly high AUC levels in a child who received intravenous busulfan before stem cell transplantation

    T Nishikawa, Y Okamoto, T Tanabe, Y Shinkoda, Y Kodama in Bone Marrow Transplantation (2010)

  8. Article

    Open Access

    Promoter CpG methylation in cancer cells contributes to the regulation of MUC4

    Mucin 4 (MUC4) is a high molecular weight transmembrane mucin that is overexpressed in many carcinomas and is a risk factor associated with a poor prognosis. In this study, we show that the DNA methylation pat...

    N Yamada, Y Nishida, H Tsutsumida, M Goto, M Higashi, M Nomoto in British Journal of Cancer (2009)

  9. Article

    Open Access

    Human papillomavirus detected in female breast carcinomas in Japan

    To investigate the aetiological role of human papillomavirus (HPV) in breast cancer, we examined the presence, genotype, viral load, and physical status of HPV in 124 Japanese female patients with breast carci...

    N A Khan, A Castillo, C Koriyama, Y Kijima, Y Umekita, Y Ohi in British Journal of Cancer (2008)

  10. Article

    Open Access

    Human papillomavirus-16 is integrated in lung carcinomas: a study in Chile

    The human papillomavirus (HPV) was detected in 20 (29%) out of 69 lung carcinomas (LCs) in Chile, by PCR and Southern blot, and was more frequently detected in squamous cell carcinoma (SQC) than in adenocarcin...

    F Aguayo, A Castillo, C Koriyama, M Higashi, T Itoh in British Journal of Cancer (2007)

  11. No Access

    Article

    Association between the HER2 expression and histological differentiation in Wilms tumor

    Human epidermal growth factor receptors (HER) play a critical role in the branching morphogenesis of renal tubules. In the current study, we analyzed the expression of HER2 in Wilms tumor and assessed the role...

    M. Salem, Y. Kinoshita, T. Tajiri, R. Souzaki in Pediatric Surgery International (2006)

  12. No Access

    Article

    Seasonal dynamics of primary production in the pelagic zone of southern Lake Baikal

     We measured primary production by phytoplankton in the south basin of Lake Baikal, Russia, by in situ 13C-bicarbonate incubations within the period March–October in two consecutive years (1999 and 2000). Primary...

    T. Yoshida, T. Sekino, M. Genkai-Kato, N. P. Logacheva, N. A. Bondarenko in Limnology (2003)

  13. No Access

    Chapter and Conference Paper

    Clinical usefulness of multidetector CT angiography : application to the diagnosis of arterial occlusive diseases in lower extermities

    Our goal is to establish the utility of multi-detector row CT angiography (MDCTA) for evaluating arterial stenosis in patients with arterial occlusive disease of lower extremities.

    N. Hirai, R. Tanaka, Y. Hori, M. Higashi in CARS 2002 Computer Assisted Radiology and … (2002)

  14. No Access

    Article

    Sympatric speciation by sexual selection

    There is increasing evidence1,2,3,4,5,6 for the process of sympatric speciation7,8, in which reproductive isolation of species occurs without physical isolation. Theoretical models9,10,11,12,13,14 have focused on...

    M. Higashi, G. Takimoto, N. Yamamura in Nature (1999)

  15. No Access

    Chapter and Conference Paper

    Simultaneous Removal of NOx, COx, SOx and Soot in Diesel Engine Exhaust

    As a means of the eliminating the NOx component in the exhaust of diesel powered vehicles, exhaust gas recirculation (EGR) techniques have been employed rather than catalyst due to the large quantity of soot whic...

    K. Fujii, M. Higashi, N. Suzuki in Non-Thermal Plasma Techniques for Pollution Control (1993)