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Article
Retraction Note to: Id-1 stimulates cell proliferation through activation of EGFR in ovarian cancer cells
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1038/s41416-021-01322-z
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Article
PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer
Caveolin-1 has a complex role in prostate cancer and has been suggested to be a potential biomarker and therapeutic target. As mature caveolin-1 resides in caveolae, invaginated lipid raft domains at the plasm...
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Article
Open Accessγ-Tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways
Tocotrienol-rich fraction (TRF) has demonstrated antiproliferative effect on prostate cancer (PCa) cells. To elucidate this anticancer property in PCa cells, this study aimed, first, to identify the most poten...
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Article
Id-1 promotes chromosomal instability through modification of APC/C activity during mitosis in response to microtubule disruption
Id-1 (Inhibitor of DNA binding/differential-1) plays a positive role in tumorigenesis through regulation of multiple signaling pathways. Recently, it is suggested that upregulation of Id-1 in cancer cells prom...
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Article
Orphan nuclear receptor estrogen-related receptor-β suppresses in vitro and in vivo growth of prostate cancer cells via p21WAF1/CIP1 induction and as a potential therapeutic target in prostate cancer
Recent studies indicate that estrogen-related receptors (ERRs) are involved in similar estrogen receptor (ER) regulatory pathways and play roles in energy and lipid metabolism. Here, we analysed the functional...
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Article
MAD2ΔC induces aneuploidy and promotes anchorage-independent growth in human prostate epithelial cells
The mitotic arrest deficient 2 (MAD2) is suggested to play a key role in a functional mitotic checkpoint because of its inhibitory effect on anaphase-promoting complex/cyclosome (APC/C) during mitosis. The bin...
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Article
Evidence of a novel biomarker, αs1-Casein, a milk protein, in benign prostate hyperplasia
Benign prostate hyperplasia (BPH) is a common disease in elderly men. Although it is a non-malignant disease, it has a significant detrimental impact on the quality of life in patients with late-stage disease....
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Article
Open AccessRole of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells
Testicular germ cell tumour (TGCT) is the most common malignancy in young males. Although most TGCTs are sensitive to cisplatin-based chemotherapy, significant numbers of TGCT patients still relapse and die ea...
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Id-1 Protein as a New Marker for PCA
Several conclusions can be reached from the data presented. (1). Id-1 protein is an important biomarker for PCA. (2). The level of its expression is related to the malignancy of the PCA. (3). Id-1 expression leve...
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Article
Open AccessRETRACTED ARTICLE: Id-1 stimulates cell proliferation through activation of EGFR in ovarian cancer cells
Increased EGFR (epidermal growth factor receptor) expression has been reported in many types of human cancer and its levels are positively associated with advanced cancers. Recently, upregulation of Id-1 (inhi...
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Article
Epstein–Barr virus latent membrane protein 1 (LMP1) upregulates Id1 expression in nasopharyngeal epithelial cells
Nasopharyngeal carcinoma is closely associated with Epstein–Barr virus (EBV) infection. The EBV-encoded LMP1 has cell transformation property. It suppresses cellular senescence and enhances cell survival in va...
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Article
Id-1 expression and cell survival
The Id (inhibitor of differentiation or DNA binding) helix-loop-helix (HLH) proteins are a group of dominant negative regulators of basic HLH transcriptional factors which promote cell differentiation. Recent ...
