7 Result(s)
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Article
Open AccessMethodological guidance for the evaluation and updating of clinical prediction models: a systematic review
Clinical prediction models are often not evaluated properly in specific settings or updated, for instance, with information from new markers. These key steps are needed such that models are fit for purpose and...
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Article
Combining method of detection and 70-gene signature for enhanced prognostication of breast cancer
Studies have shown that screen detection by national screening programs is independently associated with better prognosis of breast cancer. The aim of this study is to evaluate the association between tumor bi...
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Article
Open AccessThe role of Indonesian patients’ health behaviors in delaying the diagnosis of nasopharyngeal carcinoma
With an estimated 13,000 newly diagnosed patients per year, nasopharyngeal carcinoma (NPC) is one of the most common types of cancer in males in Indonesia. Moreover, most patients are diagnosed at an advanced ...
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Article
Open AccessOptimized outcome prediction in breast cancer by combining the 70-gene signature with clinical risk prediction algorithms
Clinical guidelines for breast cancer treatment differ in their selection of patients at a high risk of recurrence who are eligible to receive adjuvant systemic treatment (AST). The 70-gene signature is a mole...
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Article
Open AccessLong-term impact of the 70-gene signature on breast cancer outcome
Several studies have validated the prognostic value of the 70-gene prognosis signature (MammaPrintR), but long-term outcome prediction of these patients has not been previously reported. The follow-up of the cons...
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Article
Open AccessMammographic screening detects low-risk tumor biology breast cancers
Overdiagnosis of breast cancer, i.e. the detection of slow-growing tumors that would never have caused symptoms or death, became more prevalent with the implementation of population-based screening. Only rough...
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Article
Inferior survival for young patients with contralateral compared to unilateral breast cancer: a nationwide population-based study in the Netherlands
To compare overall survival between women with unilateral breast cancer (UBC) and contralateral breast cancer (CBC). Women with UBC (N = 182,562; 95 %) and CBC (N = 8,912; 5 %) recorded in the Netherlands Cancer ...
